text:
Siriimu
Buno bulwadde obuleetebwa akawuka ka vayiraasi akakosa obutoffaali mu mubiri gw’omuntu obukola ku kulwanyisa endwadde ne gusigala nga gunafuye. Olw’ensonga eno, kye kava kayitibwa HIV (Human immunodeficiency virus infection. Mu mbeera eno, Siriimu bulwadde obukosa enkola n’obuttoffaali bw’omubiri obulwanyisa endwadde. Omuntu nga yakakwatibwa akawuka kano, asobola okufunamu olubu lw’ endwadde ezeekuusa ku yegu oba ssenyiga. Kino kisobola okuddirirwa ekiseera ekiwanvuko okuyitawo kyokka nga tewali kabonero konna muntu kaalaga. Obulwadde bwe bugenda bukulu mu mubiri, bw’ongera okutabangula entegeka y’omubiri ekola ku kulwanyisa endwadde ezigulumba ekireetera omuntu okuba ng’alumbibwalumbibwa endwadderwadde omuba n’ebizimba ebitatera kukwata muntu mulamu bulungi ng’obutoffaali bwe mu mubiri n’entegeka erwanyisa obulumbaganyi mu mubiri ekola bulungi.
Akawuka ka HIV okusinga kayita mu kikolwa ky’abantu eky’okwegatta ( kino kitwaliramu abeegatta mu ntegeera emanyiddwa ey’omukazi n’omusajja n’ey’ebisiyaga okugeza omusajja ne musajja munne), okufuna omusaayi mwe kaali, okuyita mu mpiso n’okuva ku maama ne kakwata omwana mu biseera omukazi w’abeerera olubuto, mu kuzaala aba mu kuyonsa. Amazzi g’omubiri gw’omuntu agamu nga amalusu n’amaziga tegasiiga HIV. Ekubbo erisooka okwekuuma akawuka ka Siriimu kuba kwekuuma mu kwettanira ebikolwa by’okwegatta mu mukwano n’okwengendereza enkozesa y’ebintu byonna ebifumita ng’empiso. Teri ddagala liwonya wadde erigema obulwadde buno, naye, waliwo enzijanjaba esobola okwettanirwa okukendeeza ku misinde akawuka gye kaddukirako mu kukosa omubiri gw’omuntu. Enzijanjaba eno esobola okuleetera ddala omuntu alina akawuka kano okubeerera ddala mu bulamu kumpi nga atakalina era n’awangaalira ddala. Newankubadde ezijanjaba y’eddagala eriweeweeza lino ku kawuka ekendeeza ku misinde akawuka kano gye keeyongerera mu musaayi gw’omuntu mu mubiri ne kitangira akalina okulumbibwalumbibwa ennyo endwadde, enzijanjaba eyinza okuba ey’obuwanana n’oluusi okutuusa obuzibu obulala kw’agyettanidde ennyo.
Abakola ku kunoonyereza ku Ndagabutonde, bagamba nti ensibuko ya siriimu/HIV ewanuuzibwa kuba mu mawanga ga Masekkati- n’Obugwanjuba ga Afrika ku nkomerero y’ekyasa ekye 19 oba entandikwa y’ekyasa ekya 20. Siriimu yasooka kwetegerezebwa kitongole kya Amerika ekikola ku kukugira n’okutangira ensaasaana y’endwadde ekya Center for Disease Control and Prevention (CDC) mu 1981 ng’aleetebwa akawuka ka HIV. Okuva Siriimu lwe yavumbulwa, asse abantu abateeberezebwa okuba mu bukadde 36 (ng’otunuuliridde omwaka 2012). Mu mwaka gwe gumu guno we gwatuukira, 2012, kiwanuuzibwa nti abantu abakunukiriza mu bukadde 35 n’emitwalo 30 be baalina akawuka kano mu nsi yonna. Siriimu assibwa mu ttuluba ly’endwadde eziyitibwa ‘’Nnabe oba Nawokeera’’ oba endwadde ezisaasaanira ettunduttundu eddene ate ng’era zisigala zikyasaasaana.
Siriimu alina engeri nkumu gy’akosezaamu ensi, okusooka ng’endwadde n’ensibuko y’okusosolebwa. Obulwadde bulina n’engeri gye bukosezzaamu ebyenfuna naddala okujojobya abantu ababa mu myaka emikozi. Wabula obulwadde bufuuse mitwe egivuddeko okusika omuguwa mu nzikiriza z’amadiini. Mu ngeri y’emu, obulwadde bussiddwaako nnyo essira naddala mu kisaawe ky’ebikisawo n’ebyobufuzi era ng’emirimu egy’ekuusa ku kunoonyereza ku bulwadde buno gissiddwaamu n’okuvujirirwa omusimbi omusuffu okuva 1981 lwe bwazuulibwa okulaba obo basobola okubowonya oba si kyo okufuna vakisini ya siriimu.
Obubonero kw’olabira[kyusa | edit source]
Akawuka ka HIV kalina emitendera esatu mwe keeyebululira nga katuuse mu mubiri gw’omuntu okutuuka lwagwa ddala ku ndiri n’ayogerwako ng’alina Siriimu. Emitendera gino gye gino wammanga: acute infection, clinical latency ne AIDS.
Obubonero obukulu obw’omuntu ali mu acute infection[kyusa | edit source]
Ekiseera ekiddirira ng’omuntu akwatiddwa akawuka ka HIV okuyita mu limu ku makubo ge twalabye waggulu ky’ekiyitibwa acute HIV. Mu kiseera kino abantu abasinga bateeganyizibwa ssenyiga n’endwadde ezimwefaanaanyiriza okumala ebbanga eriri wakati wa wiiki 2-4 kyokka nga waliwo abatabaako kintu kyonna kibabaako. Mu bantu ababa bakwatiddwa akawuka kano, ebitundu ebiri wakati wa 40 – 90 bafuna obubonero buno; omusujja, esanjabavu, omutwe ogubobba, okubutuka olususu ng’obutulututtu bulimu olusirasira, n’amabwa mu bulago n’olumu mu bitundu eby’ekyama.Abantu abamu mu kiseera kino batera n’okulumbibwalumbibwa endwadde enneegwanyize ezijja olw’okuba mu musaayi muba muyingiddemu akawuka akagwira akatali kaamu. Endwadde endala ezeekuusa ku lubuto ng’okusesema, okusinduukirirwa emmeeme n’okufuna ekiddukano. Olumu omuntu ali mu kaseera kano asobola okufuna embeera y’okusannyalalasannyalala okutonotono oluusi mu bigere n’ebitundu ebirala embeera eyitibwa Guillain – Barre Syndrome Olw’okuba obubonero obwogeddwaako waggulu tebujja mu ngeri esengekeddwa, obumu olumu tebwetegerezebwa nti bwa kawuka ka HIV. Ne mu mbeera ezimu ezirabibwa abasawo oba eddwaaliro, ziteera okuwubisibwa endwadde endala nazo olumu eziraga obubonero obwefaananyirizaako. Olw’ensonga eno, kye kiva kisembebwa eri omulwadde yenna aba atawaanyizibwa omusujja ogutasobola kunnyonnyolwa bulungi okwekengerwa olw’akawuka ka HIV.
Obubunero bw’omuntu ali mu mutendera gwa Clinical latency[kyusa | edit source]
Obubonero obusooka buddirirwa omutendera guno. N’awatali bujjanjabi bwonna, omutendera guno ogw’omuntu eyakwatibwa akawuka ka HIV gusobola okumala ebbanga eriri wakati w’emyaka 3 n’okusukka 20 ( naye ng’okusinga kitera kuba myaka nga 8). Newankubadde ku ntandikwa y’omutendera guno omuntu ayinza obutaba na kabonero konna, bwe guba gufundikira, omuntu atandika okutaataganyizibwa omusujja, okukogga, endwadde ezeekusa ku lubuto n’okulumizibwa ebinywa. Wakati w’ebitundu 50 ne 70 abantu ku mutendera guno bafuna okuzimba kw’esanjabavu , okuba kutwaliramu okuzimba kw’esanjabavu ezisukka mw’emu (mu bitundu ebitali mbalakaso) okumala ebbanga eriri wakati w’emyezi 3 – 6.
Wadde abantu abasinga abalina ekika ky’akawuka HIV-1 basobola okuzuulibwa ng’awatali bujjanjabi katuusa omuntu oyo mu mbeera y’okweyubula n’alabikira ddala nti mulwadde wa siriimu, akatundu akatono ak’abantu abamu (ebitundu 5 ku 100) basigala ng’omuwendo gw’obutaffooli bw’omusaayi obulwanyisa obulumbaganyi mu gwo (CD4 T cells) nga guli waggulu newankubadde baba tebali ku bujjanjabi bwa Antiretroviral okumala emyaka egisukka 5. Abantu abagwa mu ttuluba lino be bayitibwa ba HIV controllers oba long-term nonprogressors (LTNP). Ettuluba eddala lye ly’abantu , ababeera n’akawuka akatasobola kulabibwa oba akatono mu musaayi wadde baba tebali ku nzijanjaba ya ARVs. Bano bayitibwa elite controllers oba elite suppressors. Bano mu bantu ababa n’akawuka 300, musobola okubaamu 1 yekka.
Obubonero bw’omuntu akawuka gwe katuusizza ku ddala lya Siriimu(AIDS)[kyusa | edit source]
Omuntu agambibwa nti wa Siriimu, akawuka HIV kaba katuusizza omubiri gwe okuba nga gunafuyisiddwa ddala . Mu mbeera eno, omuntu kati aba alina ekiyitibwa Acquired Immune Deficiency Syndrome (AIDS). Eno esobola okunnyonnyolwa ng’embeera ng’obutoffaali obulwanyisa obulumbaganyi mu masaayi (CD4+ Tcells) nga zisse wansi we 200 oba okubalukawo kw’endwadde ezeekuusa ku kawuka ka HIV. Awatali bujjanjabi butuukiridde, kumpi ekitundu ky’abantu ababa n’akawuka ka HIV batuuka mu mbeera y’okuba ne Siriimu mu bbanga lya myaka 10.
Embeera eziraga omuntu atuuse mu mbeera eno ziri nga 3[kyusa | edit source]
1 Embeera esooka pneumocystis pneumonia , omuntu afuna obubonero omuli omusujjasujja, ekifuba – oluusi ekiba ekikalu, okufuna obuzibu mu kussa, okutuuyanirira ekiro n’ebirala.
2 Embeera endala ye Cachexia - Wasting Syndrome. Muno omuntu atandika okufuna obukoowukoowu, ebinywa okusereba ssaako okukogga akagenderere. Okukogga kuno kuba mu ngeri nti oli ne bw’alya atya emmere ezimba omubiri taddamu kufuna mubiri.
3 Embeera endala ye ya Esophageal Candidiasis. Muno omuntu atandika okufuna engeri y’amabwa mu mimiro. Obubonero obulala buba endwadde ezeekuusa ku mukutu ogussizibwa empeewo.
Omuntu asobola n’okutaganyizibwa eddwande enneegwanyize (opportunistic infections) eziba zireetebwa obuwuka bwa bakitiriya, vayiraasi, fungi ne parasites nga zino ziba zirwanyisibwa baserikale b’omubiri. Endwadde ezikwata omuntu ebiseera ebisinga ziba zeekuusa ku mbeera gy’aba abeeramu. Endwadde zino zisobola okukosa ekitundu ky’omubiri.
Abantu abalina Siriimu ebiseera ebisinga baba basabola okufuna kookolo eyeekuusa ku viyiraasi, nga Kaposi’s Sarcoma, Burkitt’s lymphoma, Primary Central nervous system lymphoma ne kookola wa nnabaana (cervical cancer).
Kookolo wa Kaposi’s Sarcoma y’asinga okwegiriisiza mu bantu ababa ne HIV era ng’ebitundu ebiri wakati we 10 na 20 ku 100 gwe baba naye. Ekika ekyokubiri ekya kookolo ye lymphoma, ng’ono kigambibwa yatta kumpi ebitundu 16 ku 100 ku by’abantu ababa ne HIV so ng’era ke kamu ku bubonero obusooka mu bantu ebitundu ebiri wakati we 3 ne 4 ku bazuulibwa nti balina siriimu. Ebika bya kookolo bino ebibiri birina akakwate n’ekisipi (Human herpes virus). Kookolo wa nnabaana asinga kuba mu baba ne Siriimu olw’akakwate ne viyiraasi ya Human papillomavirus. Okwongereza kw’ebyo, abantu abalina Siriimu babeera n’obubonero bw’omusujja gw’oluteentezi, okutuuyanirira (naddala ekiro), esanjabavu ezizimba, okutiitima, obunafu n’okukogga. Ekiddukano nako kabonero akeeyolekera mu bitundu 90 ku 100 eby’abantu ababeera ne Siriimu.
Ensaasaana y’akawuka ka siriimu[kyusa | edit source]
Akawuka HIV kayita mu makubo amakulu asatu: 1. Okwegatta mu by’omukwano 2. Okugatikka musaayi aba amazzi g’omubiri ng’enkwaso, 3. N’okuva ku maama ne kakwata omwana mu biseera by’olubuto, okuzaala, oba okuyonsa (Vertical transmission)
Tewali kakwate kukwatibwa kawuka kano singa omuntu akwata mu bubi bw’omuntu alina akawuka kano, eminyira, amalusu, ebikolondolwa, amaziga, entuuyo, omusulo oba ebisesemye okujjako, ng’ebintu bino bibaddemu omusaayi. Kisoboka omuntu okukwatibwa ebika bya HIV eby’enjawulo ekimanyiddwa nga superinfection.
Okwegatta[kyusa | edit source]
Ekkubo erisinga okuyitwamu okusiigibwa akawuka ka HIV, lya kwegatta mu kikolwa ky’omukwano n’omuntu aba akalina. Omuwendo gw’abasinga okufuna akawuka kano bayita mu kika ky’okwegatta ekimanyiddwa wakati w’omusajja n’omukazi (hetero sex). Wabula mu Amerika, nga tunuulidde omwaka 2009, okusaasaana kw’akawuka okuyita mu kwegatta kwali mu bantu abeenyigira mu bisiyaga era nga bano baali bakola ebitundu 64 ku 100 ku banntu bonna abaali bakwatibwa akawuka. Bw’oba otutte okwegatta kw’abantu nga tebeekuumye, kiteeberezebwa nti obulabe okukwatibwa buli lwegatta wakati w’abantu guli waggulu ebitundu 4 ku buli 10 okusinga mu mawanga agaakula mu byenfuna.
Mu mawanga amaavu, obulabe bw’okusaasanya akawuka okuva ku bakazi okudda mu basajja kiteeberezebwa kuba ebitundu 0.38% buli kikolwa ky’okwegatta lwe kibaawo bw’ogeraageranya ku kusaasanyizibwa okuva ku basajja okudda mu bakazi okuli ebitundu 0.30%.
Obulabe bw’okusaasaanya akawuka kano mu bali b’ebisiyaga kuli waggulu nga kiteeberezebwa kuba wakati w’ebitundu 1.4% - 1.7% buli kikolwa buli lw’ekibaawo (ka kibe ku musajja ku musajja (homo sexual) oba musajja ku mukazi (heterosexual). Newankubadde obulabe bw’okusaasaanya akawuka okuyita mu bikolwa by’okwenywegera (omuli n’ebitundu eby’ekyama) (oral sex), guli wansi, naye era akawuka kasobola okuyitamu okusaasaanyizibwa era nga waaliwo n’abalwadde abaali bazuuliddwa. Obulabe akawuka okusaasaanira mu kkubo lino bussibwa ku butundu wakati wa 0 -0.04%. Mu mawanga amaavu, obulabe bw’okusaasaanya akawuka kano mu kukuba obwamalaaya okuva ku bakazi okudda mu basajja guli ebitundu 2.4% buli kikolwa so nga okuva ku basajja okudda ku bakazi obulabe buli obutundu 0.05% Obulabe bw’okukwatibwa akawuka ka HIV gweyongera mu mbeera ono ng’abadde n’endwadde z’ekikaba endala (Sexually Transmitted Infections (STI)). Amabwa mu bitundu by’ekyama (Genital ulcers) ng’ongera obulabe bw’okukwatibwa akawuka kano emirundi 5. Endwadde z’ekikaba endala nga enziku, kabootongo, chlamydia, trichomoniasis ne bacterial vaginosis nazo zisobola okwongera ku bulabe bw’okukwatibwa akawuka kano newankubadde ku ssa entonotono.
Obungi bw’akawuka kano mu musaayi gw’omuntu (viral load) nakyo kikola kinene mu kusaasaanya akawuka kano mu bikolwa by’okwegatta by’ekika kyonna n’okuva ku maama okudda ku mwana. Mu bbanga ery’emyezi 2 n’ekitundu egisooka omuntu ng’akwatiddwa akawuka kano, obusobozi bwe okukasaasaanya buba emirundi emirundi 12 olw’obungi bw’akawuka akaba mu musaayi gwe. Omuntu bw’aba ali mu biseera bye ebisembayo ng’akawuka kamuli mu musaayi, obusobozi bwe okukasaasaanya buba bukubisaamu kumpi ate emirundi munaana okusingawo.
Obulabe bw’okusaasaanya akawuka mu bakuba obwamalaaya bunene, okwegatta okuli okukuluusaanyizibwa nakwo kwongera ku bulabe bw’okusaasaanya akawuka. Obuliisamaayi nabwo bw’ogera ku bulabe bw’okusaasaanya akawuka olw’ensonga nti mu mbeera eno kondomu ebiseera ebisinga tezirowoozebwako. So nga n’obulabe bw’okukwatibwa akawuka buba bw’amaanyi eri abakwatibwakwatibwa endwadde z’ekikaba olutetenzi.
Amazzi g’omubiri[kyusa | edit source]
Ekkubo ery’okubiri erisinga okuyitibwamu okusaasaanya akawuka ka HIV lya musaayi n’ebikozesebwa mu musaayi. Okusaasaanyizibwa okuyita mu musaayi kusobola kuba mu kugatta bikozesebwa ng’empiso, okufumitibwa ekintu ekisongovu wakati w’alina akawuka n’atalina, mu kugaba omusaayi n’okukozesa ebintu ebifumita ebitali bifumbe bulungi.
Obulabe okukwatibwa akawuka mu kugatta ebintu ng’empiso mu kwekuba ebiragala buli ebitundu 0.63 ne 2.4% buli kikolwa lwe kibaawo, ate obulabe oli okukwatibwa akawuka ng’afumitiddwa kintu kisongovu guli 0.3% (omuntu ng’omu mu 333) buli kikolwa lwe kibaawo, ate obulabe oli okukwatibwa akawuka ng’amusaayi gwe gutabaganye n’alina akawuka mu butanwa ne biba ebitundu 0.09% (oba omuntu 1 mu bantu 1000) buli lwe kiba kibaddewo.
Mu Amerika abeekuba ebiragala mu 2009, baali bakola ebitundu 12% ku bantu bonna abaalina akawuka era ng’ebitundu kumpi 80 ku 100 mw’abo abakozesa ebiragala balina akawuka ka HIV.
Akawuka kasaasaanyizibwa kumpi ebitundu 93 ku 100 mu musaayi mwe kaba kabadde. Mu mawanga agaakulu, obulabe bw’okusiigibwa akawuka okuyita mu kussibwaako omusaayi guli wansi nnyo (wansi w’ekitundu kimu ku kitundu ky’akakadde) olw’okwekkeenneenya omusaayi okw’ekika ekya waggulu gye kikolebwa. Ekyokulabirako, e Bungereza, obulabe buloopebwa mu muntu omu bantu obukadde 5!
Mu mawanga amaavu, ekitundu kya musaayi ogugambibwa gwe guyinza okuba nga gw’ekebejebwa obulungi (2008 we yatuukira) era kiteeberezebwa nti ebitundu 15 ku 100 ku muwendo gw’abakwatibwa akawuka kano bakafunira mu kussibwako musaayi mwe kaba n’ebintu ebyekuusa ku musaayi, nga kino kitegeeza nti ebitundu ebiri wakati w’e 5 ne 10 mu nsi yonna ey’abalina akawuka kano bakafunira mu musaayi okugagibwa.
Abantu abettanira okusalwa enjola mu bigambo kigambibwa nabo bali mu bulabe bw’okukwatibwa akawuka kano newankubadde tewali mulwadde yali afunise kuyita mu kkubo lino ali ku likodi. Ensiri n’ebiwuka ebirala kizibu okusaasaanya akawuka ka HIV.
Okuva ku maama okudda ku mwana[kyusa | edit source]
Akawuka ka HIV kasobola okusaasaanyizibwa okuva ku maama okudda ku mwana mu kiseera ky’olubuto, mu kuzaala ne mu kuyonsa. Lino ly'ekkubo ery'okusatu erisinga okusaasaaniramu akawuka mu nsi yonna. Awatali bujjanjabi, obulabe bw’okufuna akawuka ng’omukyala tannasumulukuka ne mu kusumulukuka guli ebitundu 20 ku 100 so nga mu kuyonsa obulabe buli ebitundu 35 ku 100. 2008 we yatuukira, ekkubo lino (vertical transmission) lyali livunaanyizibwa ku bitundu 90 ku 100 ku muwendo gw’abaana abaali abalina akawuka. Okuyita mu nzijjanjab ey’omulembe, obulabe bwa maama okusiiga omwana bussiddwa nnyo okutuuka ku kitundu 1 ku 100. Obujjanjabi obutangira mulimu; maama okukozesa ARVS ng’ali lubuto ne mu kuzaala, abakyala okuzaala nga balongooseddwa, maama okwewala okuyonsa n’okussa bbebi ku ddagala lya ARVs. Ebimu ku bimenyeddwa waggulu ebyembi mu mawanga agamu agakyakula tebiriiyo. Singa omusaayi gw’etabika mu mmere mu kiseera ky’okugaaya, kisobola okuleetawo obulabe bw’okusaasaanya akawuka.
Enkula ya kawuka ka HIV (virology)[kyusa | edit source]
Akawuka HIV ke kavaako embeera etuusa omuntu okulwala Siriimu. HIV kika kya viyiraasi mu butonde ekyekolako olukomera retrovirus nga mu nkula yaakyo kirumba ntegeka y’omubiri eguyamba okulwanyisa obulumbaganyi naddala obutoffaali bwa CD4+ T Cells, Macrophages ne [[dendritic cells. Mu bugenderevu ne mu butali, akawuka ka HIV kasaanyawo obutoffaali bwa CD4+ T cells.
Akawaka HIV kagwa mu ttuluba ly’ensibuko genus Lentivirus eririna akakwate ku kika Retroviridae. Vayiraasi ezimanyiddwa nga Lentivirus zifaanaganya enkula n’obutonde. Ebika by’ebisolo bikosebwa lentivirus ezivaako endwadde okumala ekiseera ekiwanvu mu mubiri okweyerula. Zisaasaanyizibwa ga lulandira olw’ekozeeko olukomera. Nga ziyingidde mu katoffaali ke buluubirira, enkula yaako yeekyusa ne yeegabanyamu. Kino nga kiwedde, kayingira ntabiro ya katoffaali k’omubiri (cell nucleus) ne katandika okukola olubembe ku katoffaali akalumbiddwa okwewala okwetegerezebwa abaserikale oba entegeka z’omubiri ezikola ku kulwanyisa obulumbaganyi mu gwo. Mu ngeri endala, akawuka katandika okweyubula okuva mu katoffaali akaalumbiddwa ne muvaamu obuwuka obulala.
Ebika bya kawuka ka HIV byawuziddwamu emirundi ebiri: HIV-1 ne HIV-2. HIV- 1 ke kawuka akaasooka okuzuulibwa (mu kusooka kaali kaayitibwa LAV oba HTLV-III]]). Kano ke kasinga okuba mu bantu era ke kavunaanyizibwa ku kufa kw’abantu abasinga mu nsi. HIV-2 kasinga kuba mu Bugwanjuba bwa Afrika.
Ensaasaana y’akawuka mu musaayi (Pathophysiology)[kyusa | edit source]
Akawuka ka HIV nga kamaze okuyingira omubiri gw’omuntu, ekiseera ekiddirira kiba kya kweyubula oba okweyalula ku misinde emiyitirivu (viral replication) ekikaleetera okuba akangi mu musaayi gw’oku ngulu. Mu biseera by’okukwatibwa akawuka kano ebisooka, obungi bw’akawuka kano butuuka mu bukadde n’obukadde mu buli (milliliter) y’omusaayi. Kino kiddirirwa okusereba kw’obungi bw’obutoffaali bwa CD4+ T Cells. Akawuka okweyalula mu bungi okuva nga kaakayingira omubiri (viremia) kirina akakwate ku kukuzuukusibwa kw’obutoffaali bwa CD8+ T Cells, ezitta obutoffaali obuba bulumbiddwa akawuka ka HIV, okweyalula kw’obutoffaali obulumbiddwa HIV ne bukyusibwakyusibwa obutonde bwabwo n'enkula (seroconversion).
Okuzuukusibwa kw’obutoffaali bwa CD8+T Cell kirowoozebwa nti kukulu mu kukuuma omuwenda gw’akawuka (HIV) mu musaayi nga gulinnya n’okukka nga bunaabwo obwa CD4+ T Cell bwe bugenda mu maaso n’okweyaluza.
Enneeyisa oba enziramu y’obutoffaali bwa CD8+T Cell mu kiseera ky’obulumbaganyi kirina akakwate ku kukendeeza emisinde akawuka ka HIV mwe keeyalulira mu musaayi newankubadde tekasaanyizibwawo (HIV).
Ku nkomerero, akawuka ka HIV kaleeta Siriimu bwe kamalawo obutoffaali bwa CD4+ T cell mu musaayi. Kino kinafuya entegeka y’omubiri erwanyisa obulumbaganyi era obutoffaali obwo we butali, omubiri tegusobola kulwanyisa bulumbaganyi bukolebwa ndwadde oba okutta obutoffaali obulala obuba bumaze okufuulibwa obw’obulabe olwa HIV okubwesogga.
Embeera obutoffaali bwa CD4+ T Cell gye busaanyizibwawo, ekyuka okusinziira ku mutendera akawuka gye kabaamu mu mubiri (kwe kugamba; we kaba kaakaguyingirira ne we kabeerera nga kamazeemu ku kiseera (acute and chronic phases)). Mu kiseera ekimanyiddwa nga (Acute phase), okulwanagana okubaawo ku butoffaali obusenseddwa akawuka ka HIV okubutta okuba kuwadaawandibwako obutoffooli obukola ogw’okutta bunnaabwo obuba bufunye obuzibu ((cytotoxic T cells)) kuleetera obutoffaali bwa CD4+ T Cell okusereba newankubadde embeera ya (apotosis) esobola okuvaako kino. Mu kiseera ekimanyiddwa nga (chronic phase) embeera y’omubiri okuba nga buli kadde guli ku bwerende nga n’okutondawo T cells kutono, kivaako omuwendo gwa CD4+ T Cells okusereba.
Newankubadde obubonero bwa Siriimu tebweraga okumala emyaka ng’omuntu amaze okukwatibwa akawuka ka HIV, omuwendo gwa CD4+ T Cells ogusinga gusaanyizibwawo mu wiiki ezisooka ng’akawuka kaakayingira mu mubiri gw’omuntu naddala mu lunyiranyira lw’ebyenda omusinga okuba obutoffaali obulwanyisa obulabe (lymphocytes).
Ensonga lwaki obutoffaali bwa CD4+ T Cell obw’olunyiranyira (Mucosal CD4+ T cells) bwe businga okwettanirwa akawuka kwe kuba nti bulaga ekiriisa CCR5 akawuka ka HIV kye kakozesa ng’omukutu (co- receptor) okwesogga obutoffaali so ng'akatundu katono nnyo aka CD4+ T Cells mu musaayi akasobola okubaako embeera y’ekiriisa ekyo.
Enkyukakyuka ezimu ku CCR5 naddala ekika kya CCR5 - ^32 zisobola okutangira okulumbibwa kw’akawuka ka HIV (HIV -1 infection).
Akawuka ka HIV kanoonya ne kasaanyawo CCR5 eziba ziraga embeera ya CD4+ T Cells mu kiseera kya (Acute infection). Obwangu entegeka y’omubiri erwanyisa endwadde gy’eyanukulamu obulumbaganyi bw'akawuka nga kamaze okuyingira omubiri kukendeeza ku bukosefu obwandikoleddwa akawuka olwo ne kireetera omubiri okuyingira ekitundu ekimanyiddwa nga (clinically latent phase).
Obutoffaali bwa CD4+ T Cells mu lunyiranyira lw’ebyenda lusigalira ddala nga lwo lumeteddwa akawuka. Akawuka okusigala nga keeyubula kireetera entegeka y’omubiri erwanyisa obulumbaganyi okusigalira ddala ng’ekola butaweera ogwayo okuyitira ddala mu kiseera ekya chronic phase.
Omubiri okubeera ku bwerende olw’okuba entegeka erwanyisa obulumbaganyi eba ezuukusiddwa ekiriisa (protein) ekitonotono ekizuukusa obutoffaali (cytokines) kiva ku kawuka okwongera okutabangula omubiri nga kagenda keeyubula.
Embeera y’obwerende eno era yeekuusa ne ku ntegeka y’omubiri eketta embeera y’olunyiranyira mu byenda okuba ng’efudde (Break down of immune surveillance system of the gastrointestinal mucosal barrier) nga kino kiba kivudde ku kusereba kwa CD4+ T cell ez’olunyirira mu kiseera kya (acute phase).
Okukebera akawuka[kyusa | edit source]
Akawuka ka HIV kazuulibwa mu kukeberebwa olwo ne kamanyibwa n’omutendera kwe kaba kalimu mu mubiri. Abakakiiko akakola ku kutangira endwadde aka United States Preventive Services Task Force kasemba abantu bonna aba wakati w’emyaka 15 – 65 ng’abakyala ab’embuto bonna kya buwaze. Okukeberebwa oba akawuka ka HIV keesozze omubiri gw’omuntu ng’embeera ya seroconversion tennabaawo kikolebwa nga bapima HIV –RNA oba p24. Ribonucleic acid (RNA) kika kya molekyu (molecule) ekikola emirimu egy’egyawulo n’okuwa ebirairo ku nneeyisa y’obutoffaali z’endagabutonde (genes). Okukebera p24 kugenderera kuzuula oba ekika ky’ekiriisa kya protein eky’akawuka ka HIV ekimanyiddwa olumu nga CA, obutoffaali bwa Monoclonol ezeekuusa ku kiriisa kya p24 byegatta mu musaayi gw’omuntu. Buli kiriisa kya p24 mu musaayi kyebeembeka ku katoffaali ka monoclonal era obutoffaali bw’ekiriisa p24 bwe kyegatta ku butoffaali monoclonal, kireetawo enkyukakyuka ya langi singa ekiriisa kiba nga kyabadd mu musaayi okukeberebwa.
Ebiva mu kukebera akawuka mu butoffaali bw’abaana abato wansi w’emyaka 18 ebiseera ebisinga ebivaamu biba bifu olw’ensonga nti baba bakyalina obutoffaali obuyamba ku mubiri obwa bamaama baabwe maternal antibodie. Mu mbeera eno okusiigibwa akawuka ka siriimu kusobola kuzuulibwa nga bakozesa PCR okuzuula RNA oba endagabutonde {DNA]] oba okuyita mu kiriisa kya p24.. Ebitundu by’ensi bingi tebirina busobozi bwa nkebera ya PRC yeesigika era nga mu bifo bingi balinda okutuusa omwana ng’akuze ekimala okukeberwa obutoffaali . Mu mawanga agali w’eddungu Sahara wakati wa 2007 – 2009 abantu abali wakati w’ebitundu 30 – 70 baali bamanyi nga bwe bayimiridde ku nsonga y’akawuka ka Sirriimu. Mu 2009, abantu wakati wa 3.6 ne 42 ku 100 mu basajja bali bakebereddwa ekyoleka nti waaliwo okweyongera mu maaso bw’ogeraageranya n’emyaka egyasooka.
Ebiti omugwa abakwatiddwa akawuka ka HIV[kyusa | edit source]
Enkola bbiri ez’ekisawo ze zeesigamizibwako okusengeka akawuka ka HIV n’endwadde ezeekuusa ku kawuka olw’okusobola okubwekenenya. Enkola esooka y’ensengeka y’ekitongole ky’Amawanga Amagatte mu nsi ekivunaanyizibwa ku byobula World Health Organisation WHO n’ensengeka y’ekitongole ky’Amerika ekivunaanyizibwa ku kutangira endwadde ekya Center for Disease Control (CDC).
Ensengeka ya CDC’s esinga kwettanirwa mu mawanga agaakula. Engeri ensengeka y’ekitongole kya WHO gy’eteetaza nnyo bizuuliddwa kuva mu labalatore, esinga kwettanirwa mu mawanga agakyakula agalina ebikozesebwa ebitono. Newankubadde ensengeka eyawukana, enkola zombi ziyamba mu kukung’aanya bwiino ku ndwadd eno.
WHO ennyinnyola ya Siriimu yasooka kugiwa mu 1986. Okuva olwo, ensengeka ezze esuumusibwa n’okugaziyizibwa, era ng’ennyinnyola ekyasembyeyo yali mu 2007. Enkola ya WHO ekozesa emitendera gino mu nseneka yaayo.
1. Primary HIV infection: Omutendera guno omuntu asobola okuba nga talaga bubonero kyokka ng’alina akawuka asymptomic oba ng’ali mu mbeera y’okufuunira lusenyigasenyiga acute retroviral syndrome
2. Siteegi 1: Tewali bubonero bulagibwa akwatiddwa era ng’obutoffaali bwe obwa CD4+ T Cell busukka 500 mu musaayi cubic mm. Ku mutendera omuntu asobola okufuna esanjabavu ezisukkiridde.
3. Siteegi 2: Obubonero obutonotono busobola okweyoleka omuba okubutukabutuka omubiri olutulututtu nga lulimu olusirasira. Wano omuwendo gwa CD4+ T Cell gukka okuva ku 500 mu buli cubic liita y’omusaayi.
4. Siteegi 3: Omutendera guno, omuntu afuna ekiddukano ekitannyonnyolekeka kwe kivudde okumala ebbanga erisukka omwezi, omuntu asobola n’okutandika okulumbibwa endwadde ezireetebwa obuwuka bwa bakitiriya omuli n’akafuba. Obutoffaali bwa CD4+ T Cell bukka wansi wa 350.
5. Siteegi 5 oba Siriimu: Embeera enzibu omuba n’okufuna obuzibu ku bwongo toxoplasmosis, okufuna Kaposi’s Sarcoma, emimiro okufuna amabwa candidiasis of the esophagus, trachea n’ebirala. Obutoffaali bwa CD4+ T Cell buba wansi 200.
Ate okusinziira ku nsengeka y’ekitongole kya CDC, emitendera gy’akawuka ka HIV gy’asemba okukyusibwa mu 2008. Enkola eno ensengeka emitendera akawuka ka siriimu gye kayisaamu omuntu nga batunuulira omuwendo gw’obutoffaali bwa CD4+ T Cell n’obubonera obweyoleka ku muntu.
Siteegi 1: CD4+ T Cell ziba zenkana 500 oba okusingawo era tewaba kabonero kooleka Siriimu.
Siteegi 2: Omuwendo gwa CD4 nga guli wakati wa 200 – 500 era tewali bubonero bulaga Siriimu.
Siteegi 3: Omuwendo gwa CD4 gwenkana 200 oba okuba wansi wagwo.
Newankubadde omuwendo gwa CD4 gulinnya okuva ku 200, okujjanjaba embeera n’obubonero bwa Siriimu kulina okusigala.
Okutangira[kyusa | edit source]
Eby’okwegatta[kyusa | edit source]
Okukozesa obupiira kukendeeza ku bulabe bw’okusaasaanya akawuka ka HIV ebitundu 80 ku 100. Singa kondomu zikosebwa abafumbo, ng’omu ku bo alina akawuka, embeera y’akawuka okusaasaanyizibwa eri ekitundu 1 ku 100. Waliwo obukakafu nti ne kondomu y’ekikyala nayo esobola okuwa obukuumi bwe bumu nga kondomu y’abasajja. Omukazi okwesiga ebizigo ebirimu eddagala lya tenofovir Reverse transcriptase inhibitor nga tanneegatta, kikeendeeza ku bulabe bw’okukwatibwa ebitundu 40 ku 100 mu bakyala mu Afrika.
Okwawukanako, okukozesa ekika ky’ebizigo ebyesiigibwa mu bitundu by’ekyama ebya spermicide nonoxyno 1-9 bino bisobola okwongera obulabe bw’okukwatibwa akawuka kano olw’ensonga nti bireetera abikozesezza okufuna okusiiyibwa mu mbugo n’okwetakulatakula. Okukomola abasajja mu kitundu ky’Afrika eky’obukiikaddyo bw’eddungu Sahara kiyambye okukkakkanya ku bulabe bw’abasajja abeenyigira mu bikolwa by’okwegatta ebimanyiddwa (hetero sexual men) okukwatibwa akawuka ka HIV, ebitundu ebiri wakati wa 38- 68 ku 100. Okusinziira okukunoonyereza okukoleddwa, ekitongole kya WHO ne UNAIDS, byonna bisemba abasajja okukomolwa ng’ekkubo ly’okukeendeza okusaasaana kw’akawuka wakati wa basajja n’abakazi mu 2007.
Eky’okukomola oba kikendeeza ku kusaasaanya kw’akawuka mu basajja n’abakazi kikoontanibwako. Mu ngeri y’emu, n’omugaso gw’okukomola mu mawanga agaakula kuliko akabuuza oba kulina ne kye kuyinza okuyamba kutangira obulabe bw’okusaasaanya akawuka mu basiyazi.
Wabula abakungu abo, balina okutya nti entaputa embi ku nsonga y’okukomola eyinza okuleetera abantu abamu okuwubisibwa ne beeyongera kwettanira bikolwa bisobola kubateeka mu bulabe bwa kukwatibwa kawuka. Omuwendo gw’abavubuka bangi bongera okwenyigira mu bikolwa ebibateeka mu bulabe bw’okukwatibwa akawuka ka HIV. Tekimanyiddwa oba okujjanjaba endwadde z’ekikaba kiyamba mu kutangira akawuka ka HIV okusaasaana.
Pre – exposure[kyusa | edit source]
Abantu abalina akawuka ka HIV nga balina CD4 ezeenkana oba eziri waggulu wa 350 okumira eddagala eriweweeza ku kawuka ka HIV antiretrovirals bwe balikozesa nga tennanneegatta na baagalwa baabwe kikendeeza ku bulabe bw’okukwatibwa akawuka ebitundu 96 ku 100. Kino kikola ebitundu ebiri wakati wa 10 – 20 ku kukeendeeza ensaasaana kw’akawuka. Okubeera ku nzijanjaba ya Pre – exposure Prophylaxis (PrEP) ne doozi y’eddagala lya tenofovir ne bwe kutabaako emtricitabine kiyamba okutangira ensaasaana y’akawuka mu basiyazi, abaagalana okuba omu ng’alina akawuka omulala nga talina, n’abavubuka abeettanira enkola y’okwegatta ennambulukufu (hetero sexual). Enzinjajaba eno esobola okuba ey’omugaso ne ku beekuba ebiragala kuba okunoonyereza kino kikulaze. Okwettanira obuyonjo mu mbeera abantu ze babeeramu ekiteeberezebwa nti kikola kinene mu kussa ensaasaanya y’akawuka ka HIV. N’okwewala okugatta ebifumita ng’empiso nakyo kikendeeza ku bulabe bw’okusaasaanya akawuka ka HIV.
Post – exposure (PEP)[kyusa | edit source]
Buno bwe bujjanjabi omuba okumira eddagala mu bbanga eriri wakati w’essaawa 48 – 72 ng’omuntu yaakamala okwesanga mu limu ku makubo agayitamu akawuka ng’ate teyeekankasa mbeera ya muntu okugeza gw’abadde yeegasse naye oba okwesanga nga yeesaze oba okwefumita omusaayi ne gwegatta ku gw’omulala mu butanwa.
Okukozesa eddagala lyokka erya Zidovudine kikeendeeza obulabe bw’okukwatibwa akawuka ka siriimu singa omuntu aba mu butanwa yeefumise empiso eyinza okubaamu akawuka ( abasawo abafumitibwa empiso mu butanwa nga bali ku mirimu enkola eno bagyettanira.)
Omwaka 2013 we gwatuukira, enzijanjaba entuufu ekkaanyiziddwaako okuyamba mu mbeera eno mu USA eba yakukozesa eddagala omuli: tenofovir, emtricitabine ne raltegravir nga lino likendeereza ddala obulabe bw’okukwatibwa akawuka.
Enzijanjaba ya PEP esembebwa eri abo ababa basobezeddwaako naddala mu mbeera ng’akoze ekikolwa amanyiddwa nti alina akawuka ka HIV kyokka nga lya ngeri singa oli aba tamanyiddwa mbeera ye ku kawuka oba akalina oba nedda. Enzijanjaba ku ddagala lino emala wiiki 4 era ng’ereetawo embeera ezitali za bulijjo eri oyo aba alikozesa ekiseera ekyo. Mu mbeera eddagala Zidovudine we likozesebwa ebitundu 70 ku 100 ku balyettanira bafuna kamunguluze, obukoowukowu, okulumwa omutwe n’ebirala.
Maama okusiiga omwana[kyusa | edit source]
Pulogulaamu z’okutangira maama okusiiga omwana we akawuka vertical transmission zikeendeeza ensaasaana y’akawuka ebitundu ebiri wakati wa 92- 99 ku 100. Kino kikolebwa mu kwettanira ezinjajaba y’eddagala ez’enjawulo omuba ekiseera maama w’abeerera olubuto ne mu kuzaala. Oluvannyuma lw’okuzaala omwana ayinza n’okuyonsebwa ku ccupa.
Singa okuliikiriza omwana kuba kwe kusaliddwaawo okukolebwa, era nga kujja kusoboka okutuukirizibwa, maama alina okuva ku by’okuyonseza ddala bbebi we. (Lwaki? Emmere n’amata agatali g’amabeere gayinza okuleetera bbebi amabwa ku lulimi oba mu lubuto ate bw’addamu okuyonka wayinza okubaawo obulabe bw’okusiigibwa akawuka) Kyokka bbebi bw’aba taliikiriziddwa, kisembebwa n’ayonkera ddala emyezi mukaaga. Singa bbebi ayonka emyezi 6 mu butuufu byagyo, n’okweyongera okwettanira enzinjajaba ya antiretroviral prophylaxis eri bbebi, kikendeeza obulabe gy’ali okusiigibwa akawuka.
Okugemesebwa[kyusa | edit source]
Mu kiseera kino, kisoboka okugambibwa nti tewali ddagala ligema siriimu oba vakisini ya siriimu. Okugezesebwa kwa vakisini ya RV 144 ebyafulumizibwa mu 2009 byazuula nti kyali kisoboka okukendeeza ku bulabe bw’ensasaana y’akawuka ebitundu 30 ku 100. Kino kyayongera okuleetawo essuubi eri bannasaayansi abakola ku kunoonyereza kwa vakisini nti osanga bannaatuuka ku buwanguzi. Okugezesa okulala ku RV 144 kukyagenda mu maaso.
Okubeerawo n’akawuka[kyusa | edit source]
Okubeerawo n’akawuka kano kyetaagisa omuntu okukozesa ebika bya ARVs okukendeeza okusaasaanyizibwa kwako. Waliwo ebika bya ARVs eby’enjawulo byonna nga bikola ku kiseera oba mutendera gwa njawula mu bulamu bw’akawuka ka HIV. (life cycle). Enzijjanjaba eyettanira okukozesa eddagala ery’enjawulo eriruubirira emitendera egy’enjawulo egy’akawuka ka HIV kwe kaba kye kimanyiddwa nga Highly Active Anti Retroviral Therapy (HAART) Obujjanjabi bwa HAART obuliwo bukola mu mulengo (cocktails) omuba waakiri eddagala lya mirundi ng’esatu ebigwa mu ttuluba lya bika (class/types) bya ARVs. Obujjanjabi bwa HAART bukendeeza ku bungi bw’akawuka mu musaayi, bukuuma omubiri n’obusobozi okulwanyisa obulumbaganyi bw’endwadde n’okutangira endwadde enneegwanize ezitera okutuusa abantu okufa.
Ebitongole bya Amerika eby’obulamu American Institutes of Health n’ebirala bisemba okuwa obujjanjabi bwa ARVs eri buli mulwadde wa siriimu. Olw’okuba waliwo obuzibu mu kulonda enzijjanjaba n’okugituukiriza mu bulambulukufu, obulabe bw’ebiyinza okuva mu butagondera mateeka okutangira ate okumerusaawo ekika ky’akawuka akagumira eddagala oba okulyebalama, ebitongole ebyo byagala nnyo n’abalwadde okwenyigira mu bujjanjabi buno era nga bissa ensira ku kwetegereza obulabe n’ebirungi eri omulwadde alina omuwendo gw’akawuka omutono mu mubiri.
Ebyafaayo by’enzijjanjaba[kyusa | edit source]
Ensibuko y’abasawo okutandika okwettanira enzijjanjaba eyeesigamiziddwa ku HAART erina emirandira oba ensibuko kuva mu lukung’ana olw’atuula wakati wa July 7 – 16, 1966 e Vancouver (Canada) olwayitibwa 11th International Conference on AIDS. Mu lukung’aana luno, David Ho, okuva mu kitongole ekinoonyereza ku siriimu ekya Aaron Diamond AIDS Research Center e New York ne George Shaw owa University of Alabama mu ttendekero ly’obusawo, baggyayo bwiino ku mbeera y’akawuka ka HIV bwe baategeeza nti omuntu akwatiddwa akawuka ka HIV, olunaku keeyaluza emirindu obuwumbi 10, ekyali kitegeeza nti eno yali ddwadde egwa mu ttuluba lya vayiro yifekisoni ekyali kitegeeza nti kaali kalian kufuna nzinjajaba ya antiviral.
Olukung’aana luno lwaddirirwa amawulire ku nsonga eno ag’omuddiringanwa okufulumizibwa mu katabo ‘The New England Journal of Medicine’ nga biwandiikibwa Hammer, Gulick ne bannaabwe abalala abakola ku mawulire g’okunoonyereza bwe baalaga omugaso ogwali mu kukozesa indinavi mu bujjanjabi bw’enkola ya HAART. Enkola y’okwettanira obujjanjabi obulimu ebika by’eddagala bisatu 3-drug therapy yettanirwa abali ku bujjanjabi bw’abakola ku balwadde abalina akawuka era ebyavaamu gwali omuwendo gw’abantu abaali batandise okufa olwa Siriimu okukka okukka okuva ku bitundu ebiri wakati we 60 - 80.
Ensengeka y’ebika(classes) by’eddagala[kyusa | edit source]
Waliwo ebika by’eddagala ebiwera kyokka byonna nga bikozesebwa mu mirengo okujjanjaba akawuka ka HIV. Enkozesa y’eddagala lino mu mulengo okutwalira awamu ky’ekiyitibwa Anti- Retroviral Therapy Eddagala lya Anti retroviral (ARV) okutwaliza awamu lisengekebwa okusinziira ku mutendera ggw’akawuka lye gutangira. Omulengo ogusookerwako gubaamu ebiti by’eddagala 2 okuli; Nucleoside Reverse Transcriptase Inhibitors (NRTIs) + Protease Inhibitors (PI) oba ebika 2, [[Nucleoside Reverse Transcriptase Inibhibitors (NRTIs) + Non – Nucleoside Reverse Transcriptase Inhibitor NNRT).
Eddagala eritangira (Entry Inihibitors/Fusion Inihibitors[kyusa | edit source]
Lino lyettanira kukalubya mbeera y’akawuka kano mwe keerippira ku butoffaali bw’omubiri gw’omuntu. Maraviroc ne Enfuvirtide bye bika ebibiri ebikyakakasiddwa ku mulimu guno. Maraviroc eruubirira kiriisa kyanirizi CCR5 ekisangibwa ku butoffaali obuyambi (human helper T Cells).
Wabula obwegendereza bulina okubaawo mu kweyambisa eddagala lino olw’obusobozi bwe liyinza okuleetawo mu nkyukakyuka y’enneeyisa y’obutoffaali bw’omubiri tropism eyinza okuvaako ate akawuka ka HIV okukyusa ne kettanira kiriisa kirala ekya CXCR4.
Mu mbeera entono, abantu abamu basobola okufuna enkukakyuka y’enneeyisa y’obutoffaali mu kiriisa CCR5 ekivaako embeera yaakyo enyanirizi okuba nga tekola, ekintu ekisobola okuleetawo obugubaasivu oba okukendeeza ku misinde ye nneeyubula y’akawuka.
Naye nga bwe kyalagiddwaako waggulu embeera eno esobola okwebalamwa akawuka ka HIV singa ate kagubira eddagala obwanga ne kabwolekeza ekiriisa CXCR4.
Okusobola okutangira akawuka ka HIV okwerippa ku lususu lw’akatoffaali (host membrane) eddagala Enfuvirtide likozesebwa.
Enfuvirtide kika kya ddagala eririna enneeyisa ya peptide eririna okumiribwa ne likola nga likolagana ne N –terminal heptad ez’ekiriisa gp41 olwo ne lisannyalaza obusimu bw’akawuka ne katasobola kukola lujegere ku butoffaali bw’omubiri ( form an inactive hetero six-helix bundle).
Nucleoside reverse transcriptase Inhibitors (NRTI)ne Nucleotide reverse transcriptase inhibitors (NtRTI)[kyusa | edit source]
Lino ddagala eririna enneeyisa ya nucleoside ne nucleotide ezitangira ekiriisa ekiyamba akawuka ka HIV okukyusa entondeka yaako RNA n’efuuka DNA.
Kwekugamba eddagala ly’ekika kya NRTIs likutula lujegere akawuka ka HIV mwe kayita okusobola okufuna embeera mwe kasobola okutandikira okweyaluliza. Eddagala litangira nucleosides endala okugenda mu maaso nga zigattang’ana okukola olujegere lumu. Kino kisoboka olw’ensonga nti mbeera nnyunzi eya 3’OH.
Ebika bino byombi bikola mu ngeri ya kuvuganya competitive substrate inhibitors. Mu bufunze kwe kugamba nti eddagala likola mu ngeri zombi, okutangira akawuka okusikirizibwa okwerippa ku katoffaali host cell n’akatoffaali obutasikirizibwa kwegatta ku kawuka.
Ebyokulabirako bya NRTIs kuliko: deoxythymidine, zidovudine, stavudine, didanosine, zalcitabine, abacavir, lamivudine, emtictabine ne tenofovir.
Non- Nucleoside reverse transcriptase inhibitors (NNRT)[kyusa | edit source]
Lino ddagala eriba n’obusobozi okuziiza ekyukakyuka y’akawuka( reverse transcriptase) nga lyekwata ku kitundu ky’ekiriisa ekiyamba ku kawuka nga keekyusa (binding to an allosteric site of the enzyme).
NNRTIs zikosa ekifo ekiriisa ky’akawuka ekikayamba okwegatta ku k’atoffaali k’omubiri (host cell) nga kaleetawo embeera y’obutabangufu (molecular arthritis).
Eddagala lya NNRTIs zisobola era okugwa mu matuluba abiri. Ettuluba erisooka (first generation) n’ettuluba ery’okubiri (second generation).
NNRTIs mu ttuluba erisooka ziruubirira ekifo kimu eky’eriisa ky’akawuka ka HIV era kyangu akawuka okufuna obugubu ne kalyebalama. Olw’okuba NNRTs mu ttuluba ery’okubiri nnyangu okukyusakyusa ebifo, lisobola okusoma enkyukakyuka y’akawuka ne likola ku mbeera mwe kaba keekyusizakyusiza.
Ebyokulabirako by’eddagala lino mulimu; nevirapine, delavirdine, efavirenz, ne rilpivirine.
Integrase inhibitors[kyusa | edit source]
Eddagala lino liziiza ekiriisa ekikolebwa akawuka ka HIV kikasobozese okwerippa ku katoffaali k’omubiri host cell. Mu mbeera eno litangira endagabutonde y’akawuka ka HIV (RA) okwesogga endagabutonde ya katoffooli k’omubiri host cell kwe kaba keerippye (ka HIV).
Mu kiseera kino eddagala eritangira ekiriisa ky'akawuka okwerippa ku mubiri gw'akatoffaaki akawuka mwe kaba kaagala okwesogga(host cell) lingi liri mu kugezesebwa clinical trial era ng’eddagala raltegravir mu ttuluba lino lye lyasooka okukakasibwa ekitongole kya FDA mu October 2007.
Eddagala eddala erimaze okuyita okugezesebwa lye, Elvitegravir.
Protease inhibitors[kyusa | edit source]
Eddagala lino litangira akatoffaali k’omubiri host cell akamaze okwesoggebwa akawuka ka HIV ne kakansesera obuteeyalula. Mu mbeera eddagala litangira obuwuka obweyalula okuba obw’omutawaana nga liremesa embeera vayiraasi yonna mwe yeetondekera n’eba ey’obulabe ng’efuna ekiriisa. Kino kiba kityo nga liremesa embeera ya cleavage of gag and gag/pol precursor proteins. Obuwuka bwonna obweyalula ng’eddagala lya Protease inhibitor liri mu mubiri buba bulemaziddwa nga tebukyali bwa bulabe. Ebyokulabirako by’eddagala lino kuliko; lopinavir, Indinavir, Nelfinavir, Amprenavir and Ritonavir.
Waliwo n’eddagala Maturation inhibitors eritangira vayiraasi ya HIV okuyita mu mitendera gy’obulamu bwayo okutuuka lw’ekula n’eba ya bulabe ng’efunye ekirungo ky’ekiriisa kya protein. Kyokka okugezesa n’okukola ebika by’eddagala lino bibiri Bevirimat ne Vivecon byayimirizibwa mu 2010.
Wabula nn’akawuka okugubira ebika ebimu eby’eddagala weeguli nnyo. Mu mbeera eno ettuluba ly’ebika by’eddagala eritangira akawuka akagubira eddagala likoleddwa.
References[kyusa | edit source]
Bisimbuddwa mu wikipidea y'Olungereza
Notes
Jump up ^ Sepkowitz KA (June 2001). "AIDS—the first 20 years". N. Engl. J. Med. 344 (23): 1764–72. doi:10.1056/NEJM200106073442306. PMID 11396444. ^ Jump up to: a b c d e f g h i j Markowitz, edited by William N. Rom ; associate editor, Steven B. (2007). Environmental and occupational medicine (4th ed.). Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins. p. 745. ISBN 978-0-7817-6299-1. Jump up ^ "HIV and Its Transmission". Centers for Disease Control and Prevention. 2003. Archived from the original on February 4, 2005. Retrieved May 23, 2006. ^ Jump up to: a b Sharp, PM; Hahn, BH (September 2011). "Origins of HIV and the AIDS Pandemic". Cold Spring Harbor perspectives in medicine 1 (1): a006841. doi:10.1101/cshperspect.a006841. PMC 3234451. PMID 22229120. Jump up ^ Gallo RC (2006). "A reflection on HIV/AIDS research after 25 years". Retrovirology 3: 72. doi:10.1186/1742-4690-3-72. PMC 1629027. PMID 17054781.


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text:
Zabbuli 139:1-2
Endagaano Enkadde nʼEndagaano Empya
Ya Mukulu wa Bayimbi. Zabbuli ya Dawudi.
139 (A)Ayi Mukama, okebedde omutima gwange,
n’otegeera byonna ebiri munda yange.
2 (B)Bwe ntuula omanya, ne bwe ngolokoka omanya;
era otegeera byonna bye ndowooza, ne bwe mbeera ewala ennyo.
Yeremiya 17:10
Endagaano Enkadde nʼEndagaano Empya
10 (A)“Nze Mukama nkebera omutima,
ngezesa emmeeme,
okuwa buli muntu ng’amakubo ge bwe gali,
ng’ebikolwa bye bwe biri.”
Bayibuli Entukuvu, Endagaano Enkadde nʼEndagaano Empya Copyright © 1984, 1986, 1993, 2014 by Biblica, Inc.® Tuweereddwa olukusa okuva mu Biblica, Inc.® Olukusa lwonna mu nsi yonna lusigalidde mu Biblica, Inc. Luganda Contemporary Bible Copyright © 1984, 1986, 1993, 2014 by Biblica, Inc.® Used by permission of Biblica, Inc.® All rights reserved worldwide.

robotstxt: allowed

filter: keep


text:
AKULIRA abakuumi ba Hon Robert Kyagulanyi Sentamu era nga yavuganya ku ntebe y’obwaPulezidenti saako n’omuyambi we amanyiddwanga Dan Magic bawonedde watono okuttibwa ab’ebyokwerinda abasazeeko akabuga ke Nazigo mu Kayunga bwe babadde nga boolekera Jinja.
Bano okukosebwa kiddiridde abaselikale ba Poliisi saako n’amaggye okusalako abawagizi ba Kyagulanyi, era amasasi ne geesooza saako ne Tiya Gaasi omuyitirivu okusaanikira Nazigo nga batangira abawagizi obutagoberera Kyagulanyi.
Mu mbeera eno abantu bangi bakoseddwa era n’akulira abakuumi ba Kyagulanyi amanyiddwanga Afande Kato akubiddwa ku mutwe ne gutiirika omusaayi, saako ne Sir Dan Magic bamukubye ennyindo saako ne mimwa bonna ne baddusibwa mu ddwaliro lya Nazigo Health Centre 111.
Afande Kato ono ye mu Poliisi eyawebwa Hon Kyagulanyi akakiiko ke by’okulonda era nga yakulira banne bonna bwe bali ku mmotoka ya Poliisi.
Olwaleero Kyagulanyi abadde alina okubeera mu Disitulikiti ye Kayunga, Jinja ne Kamuli, era nga oluvanyuma lwa bino okubaawo ebyentambula ze bibadde bikyasanyaladde.
Poliisi ebadde mu kiseera kino tenavaayo kubaako na kyeyogera ku bibaddewo.
Do you have a story in your community or an opinion to share with us: Email us at editorial@watchdoguganda.com


text:
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Intro Aah ah aah B2C Soldiers Davie Lutalo (Hehehe) Ooh Artin on the beat Hmmm! David Lutalo Nsanyuse okulaba Nakoma kukulaba ku birthday ya Nakuya Nga ndaba onkeneka, ooh oh Tudde we twakoma Munda mutima gwange walekamu omuliro Mpulira mbabuka, ooh oh Onfudde na crazy Nkankanirira mu magulu am lazy Siiga butter ku mugaati bread Kkiriza mbeere mukwano gwo friend Chorus Awo, awo Awo wennyini mukwano gwange awo Yeah yeah ah By'ebyo by'ebyo By'ebyo byennyini mukwano gwange by'ebyo Yeah yeah yeah babe Bino bye nkugamba ogenda kufunamu Bino biyamba ffembi Njagala okkirize nga teweesisenamu Bino biyamba ffembi, ooh Bye nkugamba ogenda kufunamu Bino biyamba ffembi Njagala okkirize nga teweesiseemu Bino biyamba ffembi, aah Verse II Onnyizenyize ebiwundu munda Gwe kitangaala ekingyakira buli gye ngenda Kati tondeka ku mulyango Honey wange mpeeka ku mugongo Wadde oyambadde kakondo Sirikuleka owange omulongo Oli kibala ki? Olimu kiki ekikufuula kiti? Babe, olya mmere na ki? Ebikwawulanga notaba nga bali Chorus Awo, awo Awo wennyini mukwano gwange awo Yeah yeah ah By'ebyo by'ebyo By'ebyo byennyini mukwano gwange by'ebyo Ebinuma Verse III Mbadde nkulowoozangako Nkwesunga nkulinze nga mpeke ya tulo Yeggwe queen gwe twasomangako Mu butabo bw'abalungi ow'obumwa obugonvu Yes oh, maama Ono anyuma ne bwe yesiba leesu, Yokka Feeza, oh oh Bw'ayaka tamanyi na ttabaaza Mu kwaka, yeah yeah yeah eh Hook Bino bye nkugamba ogenda kufunamu Bino biyamba ffembi (girl) Njagala okkirize nga teweesisenamu Biyamba ffembi (yeah aah) Verse IV Yeggwe boss, yeggwe doze, yeggwe nurse Yeggwe my deejay, yeggwe dance Yeggwe queen, yeggwe moon, yeggwe mars Yeggwe my future baby yeggwe nurse oh Nze ndi nsigo, baby yeggwe farmer Nze ndi kkubo, baby yeggwe driver aaah Chorus Awo, awo Awo wennyini mukwano gwange awo Yeah yeah ah Bino bye nkugamba ogenda kufunamu Bino biyamba ffembi Njagala okkirize nga teweesisenamu Bino biyamba ffembi, ooh Bye nkugamba ogenda kufunamu Bino biyamba ffembi Njagala okkirize nga teweesiseemu Bino biyamba ffembi, aah
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text:
OMUWANDIISI we kitongole ekilamuzi Esther Nambayo asabye ekitongole ekivunanyizibwa ku nzirukanya y’emirimu ku Kkooti z’eGgwanga okunonyereza ku bigambibwa nti omukozi waakyo avunanyizibwa ku kukutekateeka n’enkulakulana Fred Waninda yakakkana ku bannamawulire 2 naakuba era n’ayonoona ye kkamera zaabwe.
Okusinziira ku katambi akaakwatibwa bannamawulire kalaga nga Waninda akuba Hannington Kisakye akolera ekitongole kya Smart 24 ttivvi wamu ne munne Eri Yiga akolera ekitongole kya Salt Media, bwe baali ku kkooti ye by’obusuubuzi mu Kampala ku lw’okuna oluwedde, bwe baali bagezaako okukwata ebifananyi bya bantu abafuluma okuva mu kkooti.
“Nfunye okwemulugunya okuva mu bannamawulire abenjawulo nga bagamba nti Waninda yakuba banaabwe nga 24 omwezi guno bwe baali bakola emirimu gyabwe ku kkooti ye by’obusuubuzi bwe yali ava mu maaso g’omulamuzi Jane Elizabeth Alividza.” Nambayo bwe yategezezza.
Ono yasabye ekitongole ekilamuzi okunonyereza ku nsonga eno, era kileete bye kinaaba kifunye mu nnaku 7 zokka, olwo basalewo eky’okukolera Waninda.
Do you have a story in your community or an opinion to share with us: Email us at editorial@watchdoguganda.com


text:
Eby’omugagga Charles Olim amanyikiddwa nga Sipapa sibirungi, munnamagye Lt Gen. Proscovia Nalweyiso bw’avuddeyo ne bwiino ku nsonga y’obubbi.
Sabiiti ewedde ku Lwokutaano, Sipapa yasindikiddwa ku limanda mu kkomera e Luzira okutuusa nga 19, omwezi guno Ogwomwenda, 2022 ku misango mukaaga (6).
Kigambibwa Sipapa y’omu ku bakkondo, abenyigira mu kumenya ennyumba omugagga, munnansi wa South Sudan Jacob Arok, mu kiro kya 28 – 29, omwezi oguwedde Ogwomunaana, e Kawuku, Bunga mu bitundu bye Makindye ne batwala ebintu ebyenjawulo.
Okunoonyereza kulaga nti Sipapa ne banne batwala ebintu omuli ssente Biriyoni emu n’obukadde 600 n’okusoba, amassimu ga iPhone 4, kompyuta za Laptop ekika kya Apple 2, ebikomo bya zzaabu eby’enjawulo nga bya mukyala, ttiivi ya Flat Screen ekika kya Sumsung n’ebintu ebirala.
Sipapa kati ali Luzira
Poliisi egamba nti baasobola okweyambisa Kalifoomu, okumenya okutwala ebintu ebyo.
Wabula mu maaso g’omulamuzi wa kkooti esookerwako e Makindye Patience Tukundane, Sipapa ne mukyala we Nakiyimba Shamirah, baguddwako emisango gy’okubbisa eryannyi nga beyambisa ebiragala omuli Kalifoomu.
Munnamateeka we Abed Nassar Mundyobole agamba nti empalana n’eby’obufuzi y’emu ku nsonga lwaki Sipapa yakwatiddwa naye si musajja mubbi. Agamba bagenda kukola kyonna ekisoboka okulaba nga basaba kkooti abantu baabwe okweyimirirwa.
Munnamateeka era agamba nti ebitongole ebikuuma ddembe, tebirina bujjulizi bulaga nti ddala Sipapa yenyigira mu kubba Arok.
Awanjagidde ebitongole ebikuuma ddembe okunoonyereza lwaki Arok, yali ateeka ssente wansi w’ekitanda n’okulaga obujjulizi obulaga nti ddala ssente yazirina.
Poliisi yazuula ddoola 70,000, amassimu ga Iphone 4, laptop 3, ebikomo bya zzaabu, ennamba z’emmotoka ez’enjawulo n’ebintu ebirala mu maka ga Sipapa ku kyalo Buwate mu Monicipaali y’e Kira mu disitulikiti y’e Wakiso.
Gen. Nalweyiso
Wabula Lt Gen. Nalweyiso agamba nti amaze ebbanga nga yenyigira mu kulondoola n’okulwanyisa Sipapa.
Agamba nti y’omu kw’abo, abalagira Sipapa okugibwako abasirikale.
Lt Gen. Nalweyiso agamba nti Sipapa musajja mubbi ng’alina akabinja k’ababbi abasukka 30 abenyigira mu kubba, bayingirira abantu ne babba ssente, amassimu, Laptop, emmotoka ssaako n’ebintu ebirala.
Mungeri y’emu Lt Gen. Nalweyiso agamba nti Sipapa tewali kubuusabuusa wadde okuwayiriza, musajja mubbi.
Awanjagidde bannayuganda okuvaayo okulwanyisa abantu nga Sipapa abeyongedde obungi mu ggwanga nga beeyita kye batali.
Vidiyo
Ebirala ebifa mu ggwanga – https://www.youtube.com/watch?v=swbD5hycS4Q


text:
Amawulire
KCCA esuubiziza okulongoosa omutindo gwémpewo
Ivan Ssenabulya
May 9th, 2022
Bya Benjamin Jumbe,
Ekitongole ekitwala ekibuga, Kampala Capital City Authority bategezezza nga bwebagenda okwongera amaanyi mu kulongoosa omutnindo gw’empewo.
Amaanyi gagenda kutekebwa mu bwagagavu bwekibuga Kampala, oluvanyuma lwokulaga nti kyekimu ku bibuga ebirimu omukka omubi.
Akulira polojekiti Air Quality Management mu KCCA Dr Alex Ndyabakira agambye nti bagenda kulwanyisa ebikka ebikyamu, okusobola okukuuma obulamu bwabantu.
Kino agambye nti kyatekeddwa mu ntekateeka eyawamu gyebabaze eyamyaka 5, okugenda okutabulira emirimu.


text:
ABA Minisitule ye by’obulamu bagamba nti baagala bawebwe obudde obulala bwa nnaku 21 ze ssabiiti 3 nga bakyetegereza wamu n’okulondolera ddala ekilwadde kya Corona Virus, oluvanyuma balyoke balabe butya bwe bayinza okukituula ku nfeete mu Ggwanga lyonna.
Bano bagamba nti mu nnaku ezo 21 zijja kubamala okuzza embera mu nteeko naddala nga balondoola ababadde abalwaddde be kirwadde kino.
Dr. Atek Kagirita nga yoomu ku baweebwa eddimu mu kitongole kye by’obulamu okulwanyisa ekirwadde kya Covid 19 yategezezza nti bakyagenda mu maaso n’okukebera abateberezebwa okuba ne kirwadde kino yadde nga abamu ku balwadde bagenze bassuuka era nga baasubira okwongera okusiibula abawonye abalala 15, okuva ku 4 abasiibulwa gye buvuddeko.
Agamba nti mu nnaku endala 21 ze baagala okuwebwa nga abantu bakyakuumibwa mu kalantiini zijja kubamala okulaba nga abalwadde bonna bakolebwako saako n’okukebera abantu abalala abateberezebwa okuba n’obubonero bwe kirwadde kya covid.
“Twebaza Katonda nti abalwadde baffe bonna bagenze bassuuka era tusuubira nti mu bbanga ssi lya wala tujja kuba tubasiibula baddeyo mu maka gaabwe, era tusaba abantu baabwe baleme okubasosola kubanga bawonedde ddala era tebayinza kusiiga muntu yenna bulwadde nga abasinga bwe babadde bagamba” Dr . Kagirita bwe yagambye.
Nga 30 omwezi oguwedde Pulezidenti Museveni yateekawo kalantiini wa nnaku 14 okwetoloola e Ggwanga lyonna eziggwako olwaleero olw’okubiri ekiro, mu kawefube w’okuziyiza okusasaana kwe kirwadde kya covid.
Pulezidenti asuubirwa okwogerako eri e Ggwanga ku lw’okubiri olw’aleero ku mbeera nga bweri oluvanyuma lwe nnaku 14 okuggwako.
Do you have a story in your community or an opinion to share with us: Email us at editorial@watchdoguganda.com


text:
1TH – – Bible en mashi du Congo
Munkwa munene oku barhumisi ba Yezu na Ekleziya
bakolaga na C.D.P.C.L. Bukavu, bulya omu EBIBLIYA NTAGATIFU,
Verbum Bible, Kinshasa 1992, rhudômire binwa binji bya mashi.
AMARUBA MARHANZI MUTAGATIFU PAOLO AYANDIKIRAGA ABATESALONIKA (BANYA-TESALONIKA)
Obwofi bw’ebinwa
Muli gano maruba marhanzi-rhanzi Paolo ayandikiraga Abanya-Tesalonika omu mwâka gwa 52, ababwîzire, erhi: «1, 9 Ntâho barhadwîrhi baganîra oku mwarhuyankiriraga, n’oku mwalekaga abazimu binyu, mpu mushimbe Nnâmahanga munashige Nyamuzinda w’obuzîne n’ow’okunali, 10 munalinge oku Omulaga agaluka kurhenga empingu, olya Mugala afûlaga omu bafù, ye Yezu, orhuciza obukunizi bwayisha.»
Paolo ashib’ibwîra abatesalonika, erhi: «2,19 Bundi bulangalire buci rhugwêrhe, gandi masîma maci rhwâbone, lindi ishungwe lihi lyârhulerhere irenge embere za Nnawirhu Yezu olusiku âgaluka, aha nyuma zinyu? Neci, mw’oyo mwe irenge lirhu, mwe na busîme bwirhu.»
Paolo ali akengeza abakristu kurhi bakwânîne okulama omu kulinda oku Yezu agaluka; ebi Nnâmahanga alonza kuhika amango Omugala galuka kuli kurhujira batagatifu (5, 1; 2, 19; 3, 13; 4, 15; 5, 2; 5, 23). Co cirhumire enyigîrizo nkulu z’amaruba kuli kubwîra abakristu kurhi balinda olwo lusiku: kulama omu butagatifu, bayake eby’enshonyi, banalame omu buzigire (5, 7-8). Na ntâye omanyire olusiku n’amango Nnâhamwirhu agaluka (5,1).
1
Omusingo
1 Paolo, Silvano na Timoteyo, kuli Ekleziya y’Abatesalonikaa eri muli Nyamuzinda lshe na muli Nyakasane Yezu Kristu. Kuli mwe enshôkano n’obuholo!
Avuga Nnâmahanga omunkwa anabasîma
2 Rhurhahusa okuvuga Nnâmahanga omunkwa ngasi mango mwe mweshi nurhumire n’okummukengêra omu nsengero zirhu. 3 Ngasi kasanzi, embere za Larha Nnâmahanga, erhi kugerêreza rhugerêreza ebijiro by’obuyemêre bwinyu, n’emikolo y’obuzigire bwinyu, n’obulangalire bwinyu bukomîre, rnuli Nnawirhu Yezu Kristu.
4 Rhurhahabiri, bene wirhu bazigirwa ba Nnâmahanga, oku muli nshagi zâge. 5 Bulya Emyanzi y’Akalembe rhwamudwîrhîre birhali binwa byône, ci yali eyegemîre obuhasheb, na Muka Mutagatifu, n’oburhwâli burhalimwo bwôbac. Ninyu mwêne mumanyire kurhi rhwàli rhuyôsire muli mwe nti lyo rhummukwânana. 6 Ninyu mwarhulolerakwo olwiganyo, mwacîsêza okushusha Nyakasane, mwayankirira Oluderhod n’enshagali ya Mûka Mutagatifu, n’obwo mwàli omu malibuko manji, 7 na ntyo mwaba lwingayo oku bemêzi boshi b’e Macedoniya n’e Akaya. 8 Neci, kurhenga emwinyu Oluderho lwa Nyakasane lwayumvikîne, arhali omu Macedoniya n’omu Akaya mwône, ci na hoshi hoshi obuyemêre bwinyu muli Nyamuzinda bwàjîre irenge, na ntyo ntacicîrhamya nakuderha. 9 Ntâho barhadwîrhi baganîra oku mwarhuyankiriraga, n’oku mwalekaga abazimu binyu, mpu mushimbe Nnâmahanga munashige Nyamuzinda w’obuzîne n’ow’okunali, 10 munalinge oku Omulaga agaluka kurhenga empingu, olya Mugala afûlaga omu bafù, ye Yezu, orhuciza obukumzi bwayisha.
2
Oku Paolo ayôrhaga erhi ali e Tesalonika
1 Ninyu mwêne murhahabiri, bene wirhu, oku rhurharhamiraga busha erhi rhuyisha emwinyu. 2 Erhi rhuba rhwamalibuzibwa n’okujacirwa e Filipie, nk’oku mumanyire, Nyamuzinda wirhu arhuha oburhwâli bw’okummuyigîriza Emyanzi y’Akalembe yâge omu ntambala ndârhi la. 3 Enyigîrizo zirhu zirhali za bunywesi, nisi erhi za bugalugalu erhi bulyâlya. 4 Ci kulya kuba Nyamuzinda abwîne oku rhukwânîne, arhufumbasize Emyanzi y’Akalembe yâge; nirhu nka rhwahanûla, rhurhalonza okusimîsa abantu, ci Nyamuzinda yêne oyishi ebirhuli emurhima. 5 Na nta mango rhusag’iderha ebinwa by’okulimîriza, ninyu mwêne murhakuhabiri, erhi okujira akantu kankafulika amagene g’eby’en’igulu; Nyamuzinda ye muhamîrizi wâni muli okwo. 6 N’oli emwinyu, oli ahandi, ntasag’ibona rhwalonza okukuzibwa n’abantu, 7 n’obwo rhwankahashire okummuyêreka obuhashe bwirhu, kulya kuba rhuli ntumwa za Kristu.
Ci rhwacijira banyinyi ekarhî kinyu, rhwayôrha nka muzire walisa abana bâge n’okubashîbirira. 8 Omu buzigire bwirhu kuli mwe, rhwankalonzize rhu mmuhe, arhali Emyanzi y’Akalembe yone, ci n’obuzine bwirhu ciru, bulya mwali murhonyire bwenene emunda rhuli! 9 Mucikengîre, bene wirhu, emirimo n’emiluho yirhu: rhwakag’immuyigîriza Emyanzi y’ Akalembe ya Nnâmahanga omu kukola budufu na mûshi nti lyo rhurhazidohera ndi muli mwe. 10 Mw’oyo na Nyamuzinda mwanahamîriza kurhi rhwàli batagatifu, bashinganyanya na bêru-kwêru. 11 Muyishi bwinja oku rhwajirire ngasi muguma muli mwe nka kula omubusi ajirira abana bâge: 12 rhwakazir’immuhanûla, rhwakammuha omurhima, rhwanakammulahiriza nti olugendo lwinyu luyôrhe lukwânana Nnâmahanga wammuhamagalaga omu Bwâmi bwâge n’omu irenge lyâge.
Obuyemêre n’obushîbirizi bw’Abatesalonika
13 Co c’irhumire oku bwirhu rhwehe, rhurhahusa okuvuga Nyamuzinda omunkwa, bulya erhi muba mwamayumva Oluderho lwâge rhwammumanyîsagya, murhaluyankiriraga nka kanwa ka muntu, ci, nk’oku lunali, mwaluyankirira nka Luderho lwa Nnâmahanga. Olwo Luderho kukola muli mwe, mwe bemêzi. 14 Neci, bene wirhu, mwayankîre olwiganyo oku Ekleziya za Nyamuzinda ziri omu Yudeya muli Kristu Yezu; kulya kuba ninyu mwalibuzîbwe n’abantu b’omu cihugo cinyu nk’oku ezo Ekleziya zalibuzibagwa n’Abayahudi, 15 balyâla bayirhaga Nyakasane Yezu n’abalêbi; bâbo bo bàrhulibuzagya; barhasimîsa Nnâmahanga, banali bashombanyi b’abantu boshi. 16 Banakarhuhanza okuyigîriza abapagani mpu lyo barhacunguka; na ntyo barhahusa okuyushûla olugero lw’ebyâha byâbo. Ci lero obukunizi bwa Nyamuzinda mîra bwàbarhindagakwo.
17 Rhwehe, bene wirhu, kurhenga rhujira nsiku rhurhabonana n’amasù, ci arhali omu murhima, rhwàyumva rhukola rhucifinjire okushub’ibona obusù bwinyu, rhwànayumva rhummuduzire bwenêne. 18 Rhwanacilalira okuja emwinyu; nie ono Paolo nakuhizire kanji, ci shetani akarhutwîra omu majira. 19 Bundi bulangalire buci rhugwêrhe, gandi masîma maci rwâbone, lindi ishungwe lihi lyârhulerhere irenge embere za Nnawirhu Yezu olusiku âgaluka, aha nyuma zinyu? Neci, mw’oyo mwe irenge lirhu, mwe na busîme bwirhu.
3
Paolo arhuma Timoteyo e Tesalonika
1 Erhi rhubona rhurhacihashiri, rhwahiga okuyôrha rhwêne Atena; 2 rhwarhuma Timoteyo, mwene wirhu na murhumisi wa Nyamuzmda omu kulumîza Emyanzi y’ Akalembe ya Kristu, nti ammuzibuhye anammukomeze omu buyemêre bwinyu, 3 Iyo harhag’ijira owarha omurhima muli ago malibukof. Ninyu mwêne murhahabiri oku eco co cigabi cirhu. 4 Bulya rhuli emwinyu, rhwakag’immurhonda oku kukwânîne rhubone amalibuko; kwo byanayishirig’iba, murhakuhabiri. 5 Erhi mbona ntacihashiri nanacimurhuma nti adôse emyanzi y’obuyemêre bwinyu nti kwankanaba Omushumisig mîra ammushumikaga, n’omukolo gwirhu gube gwafîre busha.
Avuga omunkwa oku myanzi Timoteyo amudwîrhîre
6 Ci buno Timoteyo arhuhandire, arhenga emwinyu, arhudwîrhîre emyanzi minja y’obuyemêre bwinyu n’obuzigire bwinyu; arhubwîzire oku kudula mucirhudula, n’oku mucîfinja bwenêne okushub’irhulolakwo nk’oku nirhu rhucîfinja okushub’immubonakwo. 7 Ntyo, bene wirhu, omu malumwa n’omu malibuko girhu ga ngasi lubero, obuyemêre bwinyu bwarhuhîre omurhima. 8 Neci, rhuyumvîrhe rhukola rhugwêrhe emisi bulya mukomîre muli Nyakasane. 9 Rhubwîragi nirhu kurhi rhwankahash’ivuga Nyamuzinda omunkwa kuli mwe kw’aga masîma goshi rhudwîrhe rhwayumva embere za Nnâmahanga erhi mwe murhuma? 10 Budufu na mûshi erhi kushenga rhumushenga burhahusa, nti rhushub’ibona obusù bwinyu, rhunayushûle ebibulikîne omu buyemêre bwinyu. 11 Mâshi Nyamuzinda yêne, Larha na Nnawirhu Yezu, barhufukûlire enjira y’okuhika emwinyu! 12 Ninyu Nyakasane ammuyôlolose anammujire bimâna omu kuzigirana mwêne na nnene n’omu kuzigira abantu boshi nk’oku rhummuzigira! 13 Na ntyo akomeze emirhima yinyu; ayijire myêru-kwêru omu butagatifu embere za Larha Nyamuzinda, amango nnawirhu Yezu ayisha bo n’abatagatifu bâge boshi.
4
Amahano: obutagatifu n’obuzigire
1 Neci bene wirhu, rhummuhunyire rhunammuyinginzire muli Nyakasane Yezu nti mushimbe erya njira rhwammuyigîrizaya, erya njira emmuyêreka kurhi mukwânîne okuyôrha lyo musimîsa Nnâmahanga. Câbà kwo munakola muyôsire ntyo. Muhirage njira, muje embere. 2 Mumanyire bwinja marhegeko maci rhwammuhîre oku izîno lya Nyakasane Yezu. 3 Obulonza bwa Nnamahanga b’obu: muhinduke batagatifu; muleke eby’enshonyi; 4 ngasi muguma muli mwe amany’ilanga omubiri gwâge omu butagatifu n’omu bukenge, 5 arhanacicîrîkiriraga omu kuhêkwa n’amiru mabî ak’abapagani barhishi Nyamuzinda. 6 Muli okwo harhajiraga owasârhaza mwene wâbo erhi okumujira buligo; bulya Nyakasane anacîhôle kw’ebyo byoshi, nka kulya rhwammubwiragakwo rhwanakuhamîriza 7 Birhali bya nshonyi Nyamuzinda arhuhamagaliraga, ci butagatifu. 8 Na ntyo owagayaguza ago marhegeko, erhi arhali muntu agayaguzize, ci Nyamuzinda yêne, owammushobôzagya Omûka gwâge Mutagatifu.
9 Oku biyêrekire okuzigirana, nta bulagîrire mugwêrhe bw’okuyandikirwa, kulya kuba Nyamuzinda yêne wammuyigîrizagya okuzigirana mwêne na nnene, 10 erhi kwo munayôrha mujirira bene wirhu boshi b’omu Macedoniya yoshi. Rhummuhunyire nti muyushûle okuja embere, bene wirhu. 11 Mucîsêze okukarhûza, na ngasi muguma ashîbirire omulimo gwâge, munakole n’amaboko ginyu, nka kulya rhwammurhegekaga. 12 Ntyo olugendo lwinyu luyôrhe lushingânîne omu rnasù g’abali embugah, na ntâye mwalagîrirakwo.
Abazîne n’abafîre olusiku Nyakasane agaluka
13 Bene wirhu, rhurhalonza muhabe olw’abafîre, lyo murhag’ifà mutula ak’abandi barhajira bulangalirei. 14 Akaba rhuyemîre oku Yezu afîre anafûka, ntyo kwo abafîre muli Yezu nabo banayish’iba: Nyamuzinda anabahêke bo naye. 15 Okûla rhummubwîzirekwo n’obuhashe b’Oluderho lwa Nyakasane: rhwe rhucizîne, rhwe rhwâbe rhuciriho amango Nyakasane agaluka, rhurhakashokolera abafîre. 16 Bulya, oku cimanyîso, oku izù lya Malahika mukulu n’oku mushekera gwa Nyarnuzinda, Nyakasane yêne anayandagale, n’abafîre muli Kristu bo bâfûke barhanzi. 17 Okubundi nirhu, rhwe nabo omu bitu, rhuj’ishimânana na Nyakasane omu malunga; na ntyo rhwâbêre na Nyakasane ensiku zoshi. 18 Mukaz’irhûlirizanya n’ebyo binwa.
5
Okuba masu omu kulinga okuyisha kwa Nyakasane
1 Oku nsiku n’amango, bene wirhu, nta bulagirire mugwêrhe bw’okubiyandikirwa. 2 Ninyu mwêne mukumanyire bwinja: Olusiku lwa Nyaksane kwo luyisha nka cishambo c’omu budufuj. 3 Amango abantu baderhe mpu: «Murhûla na kalembe», lyo obuhanya bwâbahonere oku caligumiza, kula emikero mibishi enarhogera omukazi oli izîmi, barhakanabona oku bayâka. 4 Mwehe, bene wirhu, murhali omu mwizimya, mpu olwo lusiku lummurhibukirekwo nka cishambo. 5 Mweshi muli bana b’ obumoleke n’ab’omûshik. Rhurhali bâna ba budufu nisi erhi ba mwizimya. 6 Kuziga rhurhajaga îro ak’abandi, ci rhube masù erhikwo, rhurhanabaga badâdà. 7 Abaja îro, budufu balija, n’abalaluka, budufu balaluka. 8 Ci rhwehe, rhwe b’omûshi, rhurhabaga badâdà; rhuyôrhe rhufumbasire empenzil y’obuyemêre n’obuzigire, rhuyambale n’ensirha y’obulangalire bw’obucire. 9 Bulya Nyamuzinda arharhulemeraga bukunizi, ci mpu rhubone obucire Nnawirhu Yezu Kristu orhumire. 10 Arhufîrire mpu rhukaba rhuzîne erhi rhukaba rhurhazînim, rhulame rhulungîne naye. 11 Ntyo mukaz’irhûlirizanya mwêne na nnene, munakahânana olwiganyo lwinja, nk’okûla munajira.
Oku ababa haguma bakwânîne okuyôrha
12 Rhummuhunyire, bene wirhu, nti mukakenga balya bammuluhira, abammukulîre muli Nyakasane, banakammuhanûla.· 13 Mubazigire kwago-kwago omukolo gwâbo gurhumire. Mube n’omurhûla ekarhi kinyu. 14 Mâshi, bene wirhu rhummuhunyire nti muhanûle abalerha akavulindi, muhe abwôba omurhima, muzibuhye engonyi, munakalembera abantu boshi. 15 Mumanye hankajira owagalulira omuntu obubî oku bubî; ci ngasi mango mucihangâne okujirirana aminja mwêne na nnene, mugajirire n’abantu boshi. 16 Mukayôrha mushagalusire ensiku zoshi. 17 Mukashenga oburhahusa. 18 Oku ngasi kantu mukaz’ivuga omunkwa, bulya ntyo kwo Nnâmahanga alonza kuli mwe, muli Kristu Yezu. 19 Murhazimagyan Muka Mutagatifu; 20 murhagayaguzagya enshôkano y’obulêbi; 21 ci mulole bwinja ngasi kantu, n’ebiri binja byo muyoôrhanage. 22 Mucilange oku ngasi coshi ciderhwa cibî.
Obwanga n’omusingo 23 Nyamuzinda w’omurhûla yêne ammujire batagatifu lwoshi lwoshi, alange emyûka n’emirhima n’emibiri yinyu buzira izâbyo kuhika olusiku Nnawirhu Yezu Kristu ayisha. 24 Ommuhamagire arhatwa omu kanwa kâge, yêne ye wajira okwo. 25 Murhusengerere nirhu, bene wirhu. 26 Mulamuse bene wirhu boshi n’ehinûnugurho hitagatifu. 27 Mmuhunyire bwenêne muli Nyakasane nti aga maruba gasomerwe bene wirhu boshi. 28 Enshôkano ya Nnawirhu Yezu Kristu ebe ninyu!
a1.1 Batesalonika; Banya-Tesalonika; Bantu b’e Tesalonika
b1.5 : Buhashe bw’okujira ebisômerîne.
c1.5 oburhwâli burhalimwo bwôba: bijiro by’okumanyisa oku Mûka Mutagatrfu ye wakag’ikolêsa Paolo.
d1.6 : Oluderho, yo Myanzi y Akalembe.
f3.3 : Amalumwa n’amalibuko co cimanyiso c’omukristu osêzire omu buyemêre en’igulu.
h4.12 : Abali embuga, bo balya bahali b’omu mulala gwirhu gw’abemêzi (1 Kr 15. 12).
i4.13 : Abandi barhajira bulangalire; bo bapagani abo.
k5.5 : Abakristu balemeragwa obumoleke n’omûshi: okuyôrha rhuli omu bumoleke n’omu bulangashane bw’omûshi bwo bworhere bwirhu.
l5.8 rhuyôrhe rhufumbasire empenzi: Lola Ef 6, 14-17.
m5.10 : Rhukaba rhuli bagumaguma erhi rhukafa.
n5.19 : Okuzimya Mûka kwo kujira akantu kankahanza omukolo gwa Mûka Mutagatrfu omu mirhima yirhu.


text:
Olubereberye
Essuula 9
Katonda n'awa Nuuwa n'abaana be omukisa, n'abagamba nti Mwalenga mweyongerenga, mujjule ensi.
2 N'ekitiibwa kyammwe n'entiisa yammwe binaabanga ku buli nsolo ey'ensi, ne ku buli nnyonyi eya waggulu; era ne byonna ebijjuza olukalu, n'ebyennyanja byonna, biweereddwayo mu mukono gwammwe.
3 Buli kiramu ekitambula kinaabanga kya kulya gye muli; ng'omuddo ogumera byonna mbibawadde.
4 Naye ennyama awamu n'obulamu bwayo, gwe musaayi gwayo, temugiryanga.
5 Era omusaayi gwammwe, ogw'obulamu bwammwe, siiremenga kuguvunaana; eri buli nsolo nnaaguvunaananga: n'eri omuntu, eri buli muganda w'omuntu, n'avunaananga obulamu bw'omuntu.
6 Buli muntu anaayiwanga omusaayi gw'omuntu, omusaayi gwe guyiyibwenga abantu: kubanga mu kifaananyi kya Katonda mwe yakolera abantu.
7 Nammwe mwalenga, mweyongerenga; muzaalenga nnyo ku nsi, mweyongerenga omwo.
8 Katonda n'agamba Nuuwa n'abaana be awamu naye,
9 nti Nange, laba, nnywezezza endagaano yange nammwe era n'ezzadde lyammwe erinaddangawo;
10 era na buli kiramu ekiri awamu nammwe, ennyonyi, ente, na buli nsolo ey'ensi awamu nammwe; byonna ebiva mu lyato, buli nsolo ey'ensi.
11 Nange nnaanywezanga endagaano yange nammwe; so ebirina omubiri byonna tebikyazikirizibwa nate mulundi gwa kubiri n'amazzi ag'amataba; so tewakyabaawo mataba nate mulundi gwa kubiri okuzikiriza ensi.
12 Katonda n'ayogera nti Kano ke kabonero ak'endagaano gye ndagaana nze nammwe na buli kitonde kiramu ekiri nammwe, okutuusa emirembe egitaliggwaawo:
13 nteeka musoke wange ku kire, era anaabanga kabonero ak'endagaano gye ndagaanye n'ensi.
14 Kale olunaatuukanga, bwe nnaaleetanga ekire ku nsi, musoke anaalabikiranga ku kire,
15 nange najjukiranga endagaano yange, gye ndagaanye nze nammwe na buli kitonde kiramu ekirina omubiri kyonna; n'amazzi tegaafuukenga nate mataba okuzikiriza omubiri gwonna.
16 Ne musoke anaabanga ku kire; nange naamutunuuliranga, njijukire endagaano eteridiba Katonda gy'alagaanye na buli kitonde ekiramu ekirina omubiri kyonna ekiri mu nsi.
17 Katonda n'agamba Nuuwa nti Ako ke kabonero ak'endagaano gye nnywezezza nze na buli ekirina omubiri ekiri mu nsi.
18 N'abaana ba Nuuwa, abaava mu lyato, Seemu, ne Kaamu, ne Yafeesi: ne Kaamu ye yazaala Kanani.
19 Abo bonsatule Nuuwa be yazaala: n'abazzukulu b'abo be baabuna ensi zonna.
20 Nuuwa n'atanula okuba omulimi, n'asimba olusuku olw'emizabbibu:
21 n'anywa ku mwenge gwalwo, n'atamiira: n'akunamira mu weema ye.
22 Kaamu, ye yazaala Kanani, n'alaba ensonyi za kitaawe, n'abuulira baganda be ababiri abaali ebweru.
23 Seemu ne Yafeesi ne batoola ekyambalo, ne bakiteeka ku bibegabega byabwe bombi, ne batambula ekyennyumannyuma, ne babikka ku nsonyi za kitaabwe; era amaaso gaabwe nga gatunuulira nnyuma, ne batalaba nsonyi za kitaabwe.
24 Nuuwa n'atamiirukuka mu mwenge gwe, n'amanya omwana we omuto bwe yamukola.
25 N'ayogera nti, Kanani akolimirwe; Anaabanga muddu w'abaddu eri baganda be.
26 Era yayogera nti Mukama yeebazibwe, Katonda wa Seemu; Era Kanani abeerenga muddu we.
27 Katonda agaziye Yafeesi, Era atuulenga mu weema za Seemu; Era Kanani abeerenga muddu we.
28 Nuuwa n'awangaala amataba nga gamaze okubaawo emyaka bisatu mu ataano.
29 N'ennaku zonna eza Nuuwa zaali myaka lwenda mu ataano: n'afa.


text:
Olubereberye
Essuula 33
Yakobo n'ayimusa amaaso ge, n'atunula, era, laba, Esawu ng'ajja, n'abasajja bina wamu naye. N'agabira abaana Leeya ne Laakeeri n'abazaana bombi.
2 N'ateeka abazaana n'abaana baabwe mu maaso, n'abaddiriza Leeya n'abaana be, n'aviisaako ennyuma Laakeeri ne Yusufu.
3 Naye ye yennyini n'akulembera mu maaso gaabwe, n'avuunama emirundi musanvu, okutuusa bwe yasemberera muganda we.
4 Esawu n'addukana mbiro okumusisinkana, n'amukwata mu ngalo, n'amugwa mu kifuba, n'amunywegera: ne bakaaba amaziga.
5 N'ayimusa amaaso ge, n’alaba abakazi n’abaana; n'ayogera nti Baani bano abali naawe? N'ayogera nti Abo be baana Katonda be yawa omuddu wo olw'ekisa.
6 Abazaana ne balyoka basembera, bo n'abaana baabwe, ne bavuunama.
7 Era ne Leeya n'abaana be ne basembera, ne bavuunama: Yusufu ne Laakeeri ne balyoka basembera, ne bavunama.
8 N'ayogera nti Ekibiina ekyo kyonna kye nsisinkanye amakulu gaakyo kiki? N'ayogera nti Okulaba ekisa mu maaso ga mukama wange.
9 Esawu n'ayogera nti Bye nnina bimmala; muganda wange, by'olina bibe bibyo.
10 Yakobo n'ayogera nti Nedda, nkwegayiridde, kaakano oba nga ndabye ekisa mu maaso go, kkiriza ekirabo kyange mu mukono gwange: kubanga ndabye amaaso go, ng'omuntu bw'alaba amaaso ga Katonda, n'onsanyukira.
11 Nkwegayiridde, toola ekirabo kyange kye bakuleetedde; kubanga Katonda ankoledde eby'ekisa, era kubanga bye nnina bimmala. N'amwegayirira, n'akitwala.
12 N'ayogera nti Tukwate ekkubo tugende, nange naakukulembera.
13 N'amugamba nti Mukama wange amanyi ng'abaana tebalina maanyi, era ng'endiga n'ente eziri nange ziyonsa: era bwe balibigoba ennyo ku lunaku olumu, ebisibo byonna birifa.
14 Nkwegayiridde, mukama wange akulembere omuddu we: nange naagenda mpola, ng'okutambula kw'ensolo eziri mu maaso gange era ng'okutambula kw'abaana bwe kuli, ntuuke awali mukama wange mu Seyiri.
15 Esawu n'ayogera nti Ka nkulekere kaakano ku bantu abali nange. N'ayogera nti Si nsonga: ndabe ekisa mu maaso ga mukama wange.
16 Awo Esawu n'addayo ku lunaku olwo ng'agenda e Seyiri.
17 Yakobo n'atambula n'agenda e Sukkosi, ne yeezimbira ennyumba, n'akolera ensolo ze engo; erinnya ly'ekifo kyeriva liyitibwa Sukkosi.
18 Yakobo n'atuuka mirembe mu kibuga kya Sekemu, ekiri mu nsi ya Kanani, bwe yava mu Padanalaamu; n'asiisira mu maaso g'ekibuga.
19 N'agula ekibanja, gye yasimba eweema ye, mu mukono gw'abaana ba Kamoli, kitaawe wa Sekemu, n'ebitundu by'effeeza kikumi.
20 N'asimbayo ekyoto, n'akituuma erinnya lyakyo Ererokeyisiraeri.


text:
1그리스도 예수님을 전파하다가 갇힌 바울과 디모데는 사랑하는 동역자 빌레몬과
2자매 압비아와 또 함께 그리스도의 군인이 된 아킵보와 그대의 집에서 모이는 교회에
3하나님 우리 아버지와 주 예수 그리스도의 은혜와 평안이 함께하기를 기도합니다.
바울의 부탁
4나는 기도할 때마다 그대를 생각하며 언제나 내 하나님께 감사하고 있습니다.
5그것은 그대가 주 예수님을 굳게 믿고 모든 성도들을 사랑한다는 말을 내가 듣고 있기 때문입니다.
6그대는 믿음의 교제를 함으로써 우리가 그리스도 안에서 가진 모든 선한 것을 충분히 이해하기를 기도합니다.
7형제여, 나는 그대가 베푼 사랑으로 성도들이 용기를 얻게 되었다는 말을 듣고 큰 기쁨과 위로를 받았습니다.
8그러므로 내가 그리스도 안에서 그대가 해야 할 일을 담대하게 명령할 수도 있습니다.
9그러나 사랑하는 마음으로 그대에게 부탁하려고 합니다. 이제 나이 많아 그리스도 예수님을 위해 죄수가 된
10나 바울은 갇힌 중에 얻은 믿음의 아들 오네시모를 위해 그대에게 부탁합니다.
11그가 전에는 그대에게 쓸모없는 사람이었으나 이제는 그대와 나에게 필요한 사람이 되었습니다.
12그래서 내 심장과 같은 그를 그대에게 돌려보냅니다.
13나는 기쁜 소식을 위해 내가 갇혀 있는 동안 그를 내 곁에 두고 그대를 대신해서 나를 돕게 하고 싶었습니다.
14그러나 나는 그대의 승낙 없이는 아무것도 하고 싶지 않습니다. 이것은 그대의 선한 일이 억지가 아니라 자발적인 것이 되도록 하기 위한 것입니다.
15그가 잠시 그대를 떠나게 된 이것으로 인해서 그가 영원히 그대를 섬기게 될지도 모릅니다.
16이제부터는 그를 종으로서가 아니라 종 이상의 사랑하는 형제로 대해 주시오. 나에게 이처럼 소중한 그는 종으로서, 주님을 믿는 형제로서 그대에게 더욱더 소중할 것입니다.
17만일 그대가 나를 친구로 여긴다면 나를 대하듯 그를 반갑게 맞아 주시오.
18그가 그대에게 손해를 끼쳤거나 빚진 것이 있으면 그것을 나에게 청구하시오. 내가 다 갚겠습니다.
19내가 직접 이 글을 써서 말하지만 내가 갚겠습니다. 내가 이런 말을 하지 말아야겠지만 그대도 나에게 빚진 것이 있음을 기억하시오.
20형제여, 내가 주님 안에서 그대를 통해 기쁨을 얻게 하고 그리스도 안에서 내 마음이 평안하게 해 주시오.
21나는 그대가 내 말에 순종하리라는 것을 확신하고 또 기대 이상으로 해 줄 것을 알고 이 글을 씁니다.
22그리고 내가 머물 방도 하나 마련해 주시오. 여러분의 기도로 내가 그 곳에 갈 수 있게 되기를 바랍니다.
23그리스도 예수님을 전파하다가 함께 갇힌 에바브라가 그대에게 문안합니다.
24또 함께 일하는 마가와 아리스다고와 데마와 누가도 그대에게 문안합니다.
25주 예수 그리스도의 은혜가 여러분과 함께하기를 기도합니다.
11 a nny 9, 23; Bef 3:1 b 2Ko 1:1 c Baf 2:25Pawulo, omusibe wa Kristo Yesu, n’owooluganda Timoseewo, tuwandiikira ggwe Firemooni, mukozi munnaffe omwagalwa, 22 a Bak 4:17 b Baf 2:25 c Bar 16:5ne Apofiya mwannyinaffe, ne Alukipo mulwanyi munnaffe, n’Ekkanisa yonna ekuŋŋaanira mu nnyumba yo.
3Ekisa n’emirembe ebiva eri Katonda Kitaffe ne Mukama waffe Yesu Kristo bibeerenga nammwe.
Okusaba n’okwebaza
44 Bar 1:8Bulijjo bwe mba nga nkusabira neebaza Katonda, 55 Bef 1:15; Bak 1:4kubanga buli kiseera mpulira nga bw’olina okwagala n’okukkiriza eri Mukama waffe Yesu n’eri abatukuvu bonna. 6Nsaba nti nga bw’ogenda otegeeza abantu okukkiriza kwo, nabo kubanyweze mu bulamu bwabwe, nga bategeerera ddala ebirungi byonna ebiri mu ffe ku bwa Kristo. 77 a 2Ko 7:4, 13 b nny 20Nsanyuka nnyo era ne nziramu amaanyi olw’okwagala kwo, kubanga emitima gy’abatukuvu giziddwa buggya ku lulwo owooluganda.
Pawulo yeegayiririra Onesimo
8Noolwekyo newaakubadde era, nga nnina obuvumu mu Kristo, nga nandisobodde okukulagira okukola ekyo ky’osaanira okukola, 99 nny 1, 23naye okwagala kwange gy’oli kumpaliriza okukusaba obusabi, nze, Pawulo, kaakano akaddiye, era ali mu kkomera olwa Kristo Yesu; 1010 a 1Ko 4:15 b Bak 4:9nkwegayirira ku bikwata ku mwana wange Onesimo gwe nayamba okukkiriza Mukama waffe nga ndi mu njegere, mu busibe, 11Onesimo oyo, gye buvuddeko ataali wa mugaso gy’oli, naye kaakano nga wa mugaso nnyo gye tuli ffembi, 12gwe naaweereza gy’oli nga n’omutima gwange gujjirako, 13oyo gwe nandyagadde okwesigaliza, ampeereze nga ndi mu busibe olw’enjiri, mu kifo kyo mwe wandibadde onnyambira, 1414 2Ko 9:7; 1Pe 5:2naye ne saagala kukikola nga tonzikirizza. Saagala okole eky’ekisa olwokubanga oteekwa, wabula kikole lwa kweyagalira. 15Kiyinzika okuba nga Onesimo yakwawukanako okumala akaseera, oluvannyuma alyoke abeere naawe ebbanga lyonna, 1616 Mat 23:8; 1Ti 6:2nga takyali muddu buddu, naye ng’asingako awo, ng’afuuse owooluganda omwagalwa ennyo, na ddala gye ndi. Kaakano ajja kubeera wa mugaso nnyo gy’oli mu mubiri ne mu Mukama waffe.
1717 2Ko 8:23Obanga ddala ndi munno, mwanirize mu ngeri y’emu nga bwe wandinnyanirizza singa nze mbadde nzize. 18Obanga waliwo ekintu ekibi kye yakukola, oba ekintu ky’omubanja, kimbalirweko. 19Kino nkiwandiika mu mukono gwange nze, Pawulo, nti ndikusasula. Sijja kukugamba nti olina ebbanja lyange. 2020 nny 7Munnange owooluganda, nkolera ekikolwa kino ekiraga okwagala, omutima gwange guddemu amaanyi mu Kristo. 2121 2Ko 2:3Nkuwandiikidde ebbaluwa eno nga neesigira ddala nga kye nkusaba ojja kukikola n’okusingawo! 2222 a Baf 1:25; 2:24 b 2Ko 1:11Nninayo n’ekirala kye nkusaba; nkusaba ontegekere we ndisula, kubanga nnina essuubi, nga Katonda okusaba kwammwe ajja kukuddamu anzikirize nkomewo gye muli.
Okusiibula
2323 Bak 1:7Epafula, musibe munnange olw’okubuulira Enjiri ya Kristo Yesu, abalamusizza.
2424 a Bik 12:12 b Bik 19:29 c Bak 4:14Ne bakozi bannange bano: Makko, ne Alisutaluuko, ne Dema, ne Lukka nabo babalamusizza.
2525 2Ti 4:22Ekisa kya Mukama waffe Yesu Kristo kibeerenga n’omwoyo gwammwe.


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Ababaka Balabudde ‘BOBI WINE’
Omu kubabadde bavuganya okukirira abantu be Kyadondo yabadde amaze okukola enteekateeka okulaba ngomubaka eyalondeddwa Robert Kyagulanyi nti amuyimbira ngamuwangudde naye Kyagulanyi yamumezze nenkoona nenywa.
Ebyokuyiga byabadde bingi mu kalulu kano omuli obutagaya balonzi, nobutanyooma bavubuuka singa baba basazeewo. Bo banabyabufuzi bagamba nti nomubaka omulonde agwana okukakasa nti wabaawo enkolagana eyabuli omu anti bulijjo agali awamu gegaluma ennyama. Katulabe omusasi waffe byakunganyiza.


text:
Amawulire
Ssente z’eddagala teziriiwo
Ivan Ssenabulya
January 31st, 2021
Bya Ndhaye Moses
Minisitule yebyobulamu egamba nti wadde olukiiko lwaba minisita lwayisizza ekitees, okugula ddagala erigema ssenyiga omukambwe COVID-19, bakyalina amakubo agenjawulo gebalina okuyitamu okufuna ssente ezetagisa obukadde $ 164 okusubola okutuusa eddagala mu gwanga.
Wiiki ewedde gavumenti yalangiridde nti eddagala erigema COVID-19 lyakutuuka mu gwanga wakati wa April ne May omwaka guno, ngabantu obukadde 9 bebalubiridde okugema mu kusooka.
Mu kusooka bakugema abantu abali mu kabi okukwatibwa obulwadde okuli abakadde nabasawo.
Wabula omuwandiisi owenkalakkalira mu minisitule yebyobulamu Dr. Diana Atwine, agamba nti emitendera mingi ejirina okuyitwamu.
Okuva COVID-19 lweyakaksibwa mu gwanga mu March womwaka oguwedde 2020, abantu emitwalo 3 mu 9,314 bebalwadde atenga omutwalo 1 mu 4,114 bebawonye.
Bbo abantu 318 bebakafa COVID-19 okuva mu March womwaka oguwedde.


text:
AKAKIIKO tarafından’okulonda mu ggwanga lya Kenya olunaku lwa mande kaalangiridde Pulezidenti ow’okutaano oluvanyuma lwa kalulu akakasameeme akaakubwa ku lw’okubiri lwa sabiiti eyayita.
Birleşik Demokratik İttifak William Ruto alangiriddwa ku buwanguzi.
Ruto yafunye obululu 7.176.141 nga bye bitundu 50.49 munne yedik Raila Odinga bwe baabade ku mbilanye naafuna obululu 6.942.930 nga bye bitundu 48.6.
William Samoei Arap Ruto nga ono yabadde omumyuka ve Pulezident wa Kenya dönemi munnabyabufuzi ateerya ntama ono ye Ssenkulu we kibiina ki Birleşik Demokratik İttifak nga ya ekibiina kino yakitandika oluvanyuma lw’okukizuula nti abadde mukamattaawe fuikaye 22 bamaze emyaka 9 nga balinnya mu kimu.
Ruto dönemi yaliko omubaka mu lukiiko lwe Ggwanga lya Kenya olukulu wansi biz kibiina kya Jubilee Alliance okuva mu mwaka gwa 1998 okutuusa mu 2013.
Yeni bir dönem yaliko Minisita avunanyizibwa ku nsonga z’amaka ku mulembe gwa Pulezidenti Daniel Arap Moi, ne zaman ku mulembe gwa Pulezidenti Mwai Kibaki ve yali Minisita avunanyizibwa ku by’obulimi.
Obuzaale bwa Ruto
Yazaalibwa nga 21 Aralık 1966 mu kitundu kye Sambut, Kamagut, mu Ssaza lye Uasin Gishu.
Kitaawe ve Daniel Cheruiyot ve Nnyina Sarah Cheruiyot eyalabiseeko mu kulangira mutabani biz ku buwanguzi ku mande.
Ono yasomera Kerotet İlköğretim Okulu bwe yamala ekibiina eky’omusanvu ne yegatta ku Wareng Ortaokulu nga wano agamba nti bizde bunudikira okwambala ku ngatto mu bigere bye.
Yeyongerayo mu ssomero lya Kapsabet Erkek Lisesi Nandi döneminin oluvanyuma yegatta ku Ttendekero lya Nairobi Üniversitesi gye yafunira Diguli ve ayasooka mu by’obulimi n’obulunzi mu mwaka gwa 1990.
Oluvanyuma yeyongerayo naakola Diguli ey’okubiri mu kunoonyereza ku bimera çağı naakuguka ku ddaala lya PHD mu ssomo lye limu mu Nairobi Üniversitesi mu mwaka gwa 2018.
Ruto bwe yali mu Ttendekero ekkulu ve Nairobi nga asoma ajjukirwa nnyo okubeera omu ku bayimbi olmak nnyimba ze ddiini nakinku mu kwaya ve Ttendekero lino nga ekitone agamba nti yakijja ku bazabaduinius be.
Agamba nti olw’okuba yali muyimbi okukira enyonza, bwatyo yasobola okusisinkana Pulezidenti Daniel Arap Moi eyali amulabyemu omulimu omulungi gwe yakola nga ye mukulembeze ve kwaya bwatyo naamusikiriza kulyingira eby’o oku.
Ruto musajja mukozi
Ruto yaliko omusuubuzi biz nkoko ez’okulya ku nguudo ze kibuga Nairobi nga eno yasikirizibwa okwagala okuldada nga mu kiseera kino yoomu ku bantu aşağılama faamu ye nkoko ennene mu Kenya ku kyalo kye Sugoi bangai çağı aga.
Kigambibwa nti ono alina amakkampuni mangi ddala omuli ne lya mafuta emanyiddwa nga Stabex eliwadde abavubuka abayitirivu emirimu mu Kenya n’amawanga amalala mu Doğu Afrika.
Bwe yamala misomo gye ku yunivasite yasooka kusomesaako mu massomero ag’enjawulo mu bitundu bya North Rift wakati w’emyaka 1990 – 1992 nga eno yatendekerayo abaana bangi okuyimba enyimba ze ddiini mu makkanisa ag’enjawulo.
Atandika eby’obufuzi mu YK’92
Ruto araştırmadika olugendo lwe mu by’obufuzi bwe yalondebwa okubeera omuwanika mu kibiina kya YK’92 nga kino kyali kilina ekigendererwa ky’okuzza Pulezidenti Arap Mo buyinza mu mwaka gwa 1992 ngai ku olwo te okuya
Emirundi mingi yagezaako okulwana okuyingira obukulembeze bwe kibiina kya KANU ekibiina ekyali mu buyinza ebiseera ebyo kyokka n’alemwa ekyamuleetera okwesimbawo nga omuntu ku kifo ky’obubaka mu 1997ekyewunyisa nawangula Reuben Chesire musajja wa Pulezidenti Moi eyali amaze ebbanga eddene nga yakulembera ekitundu kya Uasin Gishu.
Wano Pulezidenti Moi yayongera okumwesiga dönemi naamulonda okufuuka Minisita dönemi naamusembeza okumpi ve Uhuru Kenyatta gwe yali alowooza okumuddira mu büyük ekiseera ekyo.
Mu Ocak wa 2006 Ruto yalangirira nga bwagenda okuvuganya ku kifo ky’obwaPulezidenti mu Ggwanga lya Kenya mu kulonda okwali kugenda okubaawo mu mwaka 2007 olwo nga yegasse ku kibiina kya ODM dönemi ne bagenda mu kamyubul o ya kibiauldingwomwe Raila naafuna 2,656 dönemi nazalawo okuwagira Raila Odinga oluvanyuma eyawangulwa Mwai Kibaki mu Aralık ve 2007 wabula Odinga ne banne ne bagaana okukkiriza ebyava mu kulunda.
Oluvanyuma Kibaki ne Odinga bakkiriziganya okutondawo enkola ey’okugabanya obuyinza dönemi Ruto eyali amaze okufuna ekifo mu lukiiko lwe Ggwanga olukula nga akiikirira ekitundu kya Eldoret Kuzey yawebwa obwa minibulsiimi bwe tarafından 2013.
Yakolako nga Pulezidenti ow’ekiseera
Ruto yaliko omukulembeze ve Kenya ow’ekiseera okuva nga 5 okutuusa nga 8 Ekim 2014 mu kiseera Pulezidenti Uhuru Kenyatta gwe yali amyuka bwe yatwalibwa mu kkooti ve Nsi yonna olw’ebikolobero eby’akolebwa kul ku bannaNsi muon 2013.
Nga 6 Ekim 2014, Ruto yalondebwa mu butongole okufuuka omumyuka ve Pulezidenti dönemi ne mu Ağustos 2017 dönemi naddamu okulondebwa mu kifo kye kimu.
Olugendo lwe okufuuka Pulezidenti ve Kenya
Mu Aralık 2020 Ruto yalangirira nga bwagenda okwesimbawo ku bukulembeze bwe Ggwanga lya Kenya era ye ne banne ne batondawo omukago gwa United Demokratik İttifak partisi oluvanyuma lw’okukizuula nti munne bwe baali bakulembedde bannaKenya okuma ematta yagi okuravuemazu hayır Raila Odinga.
Agamba nti kin o yali akisuubira olw’ensonga nti ye baamulabanga nga omuntu atalina musingi mugumu mu byabufuzi okuva mu kika kye çağı nga bamunyooma.
Engombo kwazze atambuliza kkampeyini ze mubaddemu nti Kenya kye kiseera okufuna omukulembeze nga mwana ve munaku kubanga abagagga bawereddwa omukisa okufuga ebbanga ddene.
Topluluğunuzda bir hikayeniz veya bizimle paylaşmak istediğiniz bir fikriniz mi var: [email protected] adresinden bize e-posta gönderin.
Kaynak : https://www.watchdoguganda.com/news/politics/20220816/141455/biibino-ebyafaayo-bya-william-samoei-arap-ruto-pulezidenti-wa-kenya-omuggya-muyimbi-nakinku.html


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1
Olukano lw'ohuloongwa
1Muhuchaaka, Nasaae yaloonga ekulu neende esyaalo. 2Esyaalo syali nisibulaho efwaani yoosi haandi syali esihaya. Esiirima syali nisyabwiiha esyaalo syoosi, nae Mwooyo wa Nasaae yali nang'alaalaanga sa hu maachi.
3 #
2 Kor 4:6. Nasaae yeemao yaboola ati, “Lehe obulafu bubeeo” mani obulafu nibubaao. 4Nasaae yabona ati obulafu bwali obulai. Nasaae yakabula obulafu ohutula hu siirima. 5Nasaae yalaanga obulafu ati “Esideete,” nae esiirima Yaasilaanga ati “Esiro”. Mani nibwiira haandi nibuhya, oludaalo lutaangira.
6 #
2 Pet 3:5. Nasaae haandi yaboola ati, “Lehe libeeo ekulu elikabulamo amaachi amahabi kabiri.” 7Mani Nasaae yahola ekulu lyaakabulamo amaachi akali aakulu neende amaachi akali aasi. Mani nibiba bityo. 8Nasaae yalaanga aakulu ati “Ekulu”. Mani nibwiira haandi nibuhya, oludaalo lwohubiri.
9Haandi Nasaae yaboola ati, “Lehe amaachi kali aasi w'ekulu kebuusire abuundu alala, haandi lehe eloba lyoomu libonehe.” Mani nibiba bityo. 10Nasaae yalaanga eloba lyoomu ati “Esyaalo”, nae amaachi akebuusira abuundu alala yakalaanga ati, “Enyaanja”. Nasaae yaabona ati esyo syali esilai syeene. 11Haandi Nasaae yaboola ati, “Lehe esyaalo simereho ebimera, emisaala ekyaamaho eemwo, neende emisaala eky'ebyaamo ekyaamaho ebyaamo ebirimo eemwo, buli kutula neende efwaani yakwo hu syaalo.” Mani nibiba sa bityo. 12Esyaalo syameraho ebimera biindi koti, emisaala kyaamaho eemwo ohweema hu ngeri yaakyo, neende emisaala kyaamaho ebyaamo birimo eemwo buli kutula neende engeri yakwo mani Nasaae yaabona byoosi nibiri ebilai. 13Mani nibwiira haandi nibuhya, oludaalo lwohudatu.
14Haandi Nasaae yaboola ati, “Lehe obulafu bw'aakulu muukulu bukabuhanie esideete neende esiro; haandi lehe bube obulolero bweekesa obwiire neende endaalo neende emyaaka, 15haandi lehe obulafu obw'aakulu muukulu buhoseenge hu syaalo.” Mani nibiba bityo. 16Nasaae yahola obulafu buhoongo obw'amahabi kabiri, obulafu obuhiramo obuhoongo ohutukaanga esideete, nae obulafu buhiramo obudiidi ohutukaanga esiro. Haandi Nasaae n'aloonga eng'ining'ini chosi. 17Nasaae n'achita aakulu muukulu ohuhosaanga obulafu hu syaalo, 18ohutukaanga esideete neende esiro, haandi ohukabulaanga obulafu ohutula hu esiirima. Nasaae naabona ati esyo syali esilai. 19Mani nibwiira haandi nibuhya, oludaalo lwoohune.
20Haandi Nasaae yaboola ati, “Lehe amaachi kabeemo obuduhunyi bw'ebiloonge bilamu, haandi lehe amayoni kabburuheenge aakulu w'esyaalo nikahalania aakulu mu kulu.” 21Haandi Nasaae yaloonga ebisolo bihoongo byomu maachi neende buli siloonge silamu esikeenda, ebyeechula mu maachi, buli situla neende engeri yasyo, haandi yaloonga buli yoni libburuha, buli litula neende engeri yaalyo. Mani Nasaae yaabona ati esyo syali esilai sa. 22Nasaae yabiberesa ehabi n'aboola ati, “Mwiibulane mani mwemeede, mwiichuse amaachi akomu nyaanja haandi lehe amayoni keengiye hu syaalo.” 23Mani nibwiira haandi nibuhya, oludaalo lwohutaanu.
24Haandi Nasaae yaboola ati, “Lehe esyaalo sibeeho ebiloonge bilamu buli situla neende engeri yasyo: Ebyaayo neende ebiindu byaambaaka neende ebisolo byohu syaalo, buli situla neende engeri yasyo.” Mani nibiba sa bityo. 25Haandi Nasaae yaloonga ebisolo byohu syaalo buli situla neende engeri yasyo, haandi yaloonga ebyaayo buli situla neende engeri yasyo, haandi buli siindu syaafula hu loba buli situla neende engeri yasyo. Mani Nasaae yaabona ati ebyo syosi byali ebilai byeene.
26 #
1 Kor 11:7. Haandi Nasaae yaboola ati, “Lehe huloonge abaandu mu fwaani yeefwe, batufwaanane; haandi lehe babe neende obunyala bw'ohutuka eng'eeni chomu nyaanja, amayoni kabburuha, neende hu buli byaayo, neende hu syaalo syoosi, neende hu buli siindu syaambaaka syoosi esiri hu syaalo.” 27#Huc 5:1,2; Mat 19:4; Mrk 10:6. Nasaae yaloonga abaandu mu fwaani yae yeene. Mu fwaani ya Nasaae, Nasaae yaloonga abaandu; omusaacha neende omuhasi, Nasaae yabaloonga. 28Nasaae yaababeresa ehabi, n'ababoolera ati, “Mwiibulane mani mwiingiye, mwiichule esyaalo, haandi musituke. Haandi mube neende obunyala bw'ohutuka eng'eeni chomunyaanja, neende amayoni kabburuha, neende hu buli siindu silamu syoosi esikeenda hu syaalo.” 29Nasaae n'aboola ati, “Bone, mbao mbabereese buli musaala okwaamaho emwo, okuli mu syaalo syoosi, neende buli musaala okuli neende emwo mu byaamo byakwo; kuchia ohubechaanga ebyohulya byeeng'we. 30Haandi buli solo yiri hu syaalo neende buli yoni libburuha, neende buli siindu syaambaaka hu syaalo, buli siindu silamu siyeera, mbibereese ebimera ohuba ebyohulya byabyo.” Mani nisiba sityo. 31Nasaae naabona buli siindu si yali naloongere mani bone, syaaba esilai muno. Mani nibwiira haandi nibuhya, oludaalo lwohusaasaba.


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Abaalondebwa okukulira akakiiko akagaba e mirimu mu Disitulikiti ye Mukono bakyalemeddwa okuyingira zi offiisi zaabwe okutandika okukakkalabya emirimu, nga kigambibwa nti entabwe eva ku sipiika kulemererwa 22 yi sipiika kulemererwa eb sipiiko wa ku05.
Büyük bir aşk yaşıyorsanız, bu çok iyi bir şey değil. Sentebe.
Okuva ku lunaku olwo obutakkanya wakati wa Ssentebe Bakaluba saako n’omukubiriza w’olukiiko lwa Disitulikiti Betty Nakasi bweyongera, nga kino kyavaako Sipiika obutawereza mannya mu minisitule ye bye mirimu (Public service Ministry) gatunulwemu okulaba oba abaalondebwa basaanidde n’oluvanyuma batandike emirimu gyabwe mu butongole.
Mu kiseera kino offiisi za kakiiko akagaba emirimu ku Disitulikiti nzigale olw’ensonga nti abalina obuvunanyizibwa okuzituulamu okuwandiika saako n’okusunsula abalina okufuna emirimu bakyali bbali.
Kino kileseewo abamu ku bakulembeze okwemulugunya eri omukubiriza w’olukiiko lwa Disitulikiti Betty Nakasi gwe bagamba nti alabika alemeddwa okukola emirimu gye, wabula alwana ntalo olw’okuba abantu olw’okuba abantu olmak ayagala bayitewo.
Kkansala Stanely Muwonge akiikirira e Gombolola ye Kyampisi ategezezza nti bbo nga abakulembeze baakola omulimu gwabwe okuteekako olukiiko olugaba emirimu, nti kyokka kibewunyisa okulba nti nti nga imannyaokutuuu’nun katabaku u u u u u u u u t u k u t u t u u u u u u d u u u u u u t u t u d uuuuuuuuuuu
“Tetumanyi entalo e Mukono ddi bwe ziriggwawo kubanga buli kimu kyesibye, abaana baffe baagala okufuna emirimu, omuli Abasawo, abasomesa, ne zi offiisi endala omuli abantu abaawummula, kyokka nga kyetaagisa kakiiko okusooka okubaawo olwo emirimu egyo girangibwe mu mawulire abalina obusobozi bagisabe” Muwonge bwe yagambye.
Sipiika Betty Nakasi, ebegümeci kisigaliddwa ku nsonga zino ategezezza nti eby’ogerwa ssi bituufu nagamba nti omulimu gwe yagukola empapula n’aziteekako emikono nga kati kisigalidde akulira abagakozi okuzitwala.
Akulira abakozi James Nkata ku nsonga eno agambye nti Sipiika bwaba nga yateeka emikono ku biwandiiko yakikola ku lwakusooka wiiki eno e nga abadde taliiwo nga ali ku mirimu emitongole, naasubiza okudye aabita
Okunonyereza kulaga nti Disitulikiti ye Mukono yetaaga abakozi ba Gavumenti abasoba mu 200 nga muno mulimu abagenda okutwala offfiisi ez’enjawulo mu Belediye Meclisleri empya 5, Abasawo abasinga baawummula nga bakuliriako mu’naka.
Topluluğunuzda bir hikayeniz veya bizimle paylaşmak istediğiniz bir fikriniz var mı: Bize [email protected] adresinden e-posta gönderin.
Kaynak : https://www.watchdoguganda.com/news/20220608/137812/mukono-akakiiko-akagaba-emirimu-akaalondebwa-ssentebe-kakyalemeddwa-okutandika-okukola.html


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Ssaabalamuzi Alfonse Owiny-Dollo agaanye okuva musango gwa Pulezidenti w’ekibiina ki NUP Robert Kyagulanyi Ssentamu (Bobi Wine) gwe yatwala mu kkooti ensukkulumu.
Kyagulanyi yaddukira mu kkooti ensukkulumu okuwakanya obuwanguzi bwa ssentebe w’ekibiina ki NRM Yoweri Kaguta Museveni ku bukulembeze bw’eggwanga lino mu kulonda okwaliwo omwezi oguwedde nga 14, Janwali, 2021.
Wabula olunnaku olw’eggulo, Kyagulanyi yalagidde bannamateeka be okwanguwa okuggyayo omusango mu kkooti.
Mu kuggyayo omusango Kyagulanyi yagambye nti kkooti eremereddwa okulaga nti betengeredde mu ntambuza y’emirimu, oluvanyuma lw’okutwala omusango mu kkooti, Ssaabalamuzi Alfonse Owiny-Dollo, yakasisinkana Museveni emirundi 3.
Mungeri y’emu yagambye nti omuntu yenna okuwangula omusango mu kkooti, alina okuba ng’alina obujjulizi kyokka kkooti ensukkulumu, yamulemesezza okutwala obujjulizi mu kkooti nga tewali nsonga yonna, lwaki basigala mu kkooti nga tebasuubira mazima na bwenkanya.
Newankubadde Kyagulanyi ne bannamateeka be bali mu ntekateeka ez’okuggya omusango mu kkooti, munnamateeka Male Mabirizi, naye abadde mu kkooti y’emu ku nsonga y’okusaba Ssaabalamuzi Owiny-Dollo okulangirira nti avudde musango gwa Kyagulanyi.
Munnamateeka Mabirizi ezimu ku nsonga zabadde awa mu kkooti, agamba nti mu kulonda kwa 2006, Ssaabalamuzi Owiny-Dollo yali munnamateeka wa Museveni, munna FDC Dr. Kizza Besigye bwe yali aduukidde mu kkooti ensukkulumu okuwakanya ebyali bivudde mu kulonda kw’omukulembeze w’eggwanga.
Agamba nti Ssaabalamuzi Owiny-Dollo okubaako munnamateeka wa Museveni tasobola kwetengerera ku nsonga ezigenda mu maaso mu kkooti ezimu omuli n’omusango gwa Kyagulanyi.
Wabula Ssaabalamuzi Owiny-Dollo agaanye okuva musango era asuubiza okuwa ensonga ze gye buggya mu maaso.


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2 Ebyomumirembe
Essuula 1
Awo Sulemaani mutabani wa Dawudi n'anywezebwa mu bwakabaka bwe, Mukama Katonda we n'aba naye, n'amugulumiza nnyo.
2 Sulemaani n'ayogera ne Isiraeri yenna, abaami b'enkumi n'ab'ebikumi n'abalamuzi na buli mukulu mu Isiraeri yenna, emitwe gy'ennyumba za bakitaabwe.
3 Awo Sulemaani n'ekibiina kyonna wamu naye ne bagenda mu kifo ekigulumivu ekyali e Gibyoni; kubanga eyo ye yali eweema ya Katonda ey'okusisinkanirangamu, Musa omuddu wa Mukama gye yakola mu ddungu.
4 Naye essanduuko ya Katonda Dawudi yali agirinnyisizza n'agiggya e Kiriyasuyalimu n'agireeta mu kifo Dawudi kye yagitegekera: kubanga yali agikubidde eweema e Yerusaalemi.
5 Era nate ekyoto eky'ekikomo Bezaaleri mutabani wa Uli mutabani wa Kuuli kye yakola kyali eyo mu maaso g'eweema ya Mukama: Sulemaani n'ekibiina ne bagendanga gye kiri.
6 Sulemaani n'ayambukayo eri ekyoto eky'ekikomo mu maaso ga Mukama ekyali ku weema ey'okusisinkanirangamu, n'aweerayo okwo ebiweebwayo ebyokebwa lukumi.
7 Mu kiro ekyo Katonda n'alabikira Sulemaani, n'amugamba nti Saba kye mba nkuwa.
8 Sulemaani n'agamba Katonda nti Walaga Dawudi kitange ekisa kingi, n'onfuula kabaka mu kifo kye.
9 Kale, ai Mukama Katonda, ekigambo kye wasuubiza Dawudi kitange kinywezebwe: kubanga onfudde kabaka w'abantu abafaanana enfuufu ey'oku nsi obungi.
10 Mpa nno amagezi n'okumanya, nfulumenga nnyingirenga mu maaso g'abantu bano: kubanga ani ayinza okusalira emisango abantu bo bano abenkanidde awo obukulu?
11 Katonda n'agamba Sulemaani nti Kubanga ekyo kibadde mu mutima gwo, so tosabye bugagga, ebintu, newakubadde ekitiibwa, newakubadde obulamu bw'abo abakukyawa, so tosabye kuwangaala; naye weesabidde amagezi n'okumanya, osalirenga emisango abantu bange, be nkufuulidde kabaka:
12 amagezi n'okumanya oweereddwa; era ndikuwa n'obugagga n'ebintu n'ekitiibwa by'atabanga nabyo n'omu ku bassekabaka abaakusooka, so tewaliba oluvannyuma lwo aliba nabyo.
13 Awo Sulemaani n'ava ku lugendo lwe n'ajja eri ekifo ekigulumivu ekyali e Gibyoni, ng'ava mu maaso g'eweema ey'okusisinkanirangamu, n'ajja e Yerusaalemi; n'afuga Isiraeri.
14 Sulemaani n'akuŋŋaanya amagaali n'abeebagala embalaasi: era yalina amagaali lukumi mu bina n'abeebagala embalaasi kakumi mu enkumi bbiri, be yateeka mu bibuga eby'amagaali n'awali kabaka e Yerusaalemi.
15 Kabaka n'afuula ffeeza ne zaabu mu Yerusaalemi okuba ng'amayinja obungi, okuba ng'amayinja, n'emivule yagifuula okuba ng'emisukomooli egiri mu nsenyi obungi.
16 Era embalaasi Sulemaani ze yalina baaziggyanga mu Misiri; abasuubuzi ba kabaka ne baziweebwanga bisibo, buli kisibo n'omuwendo gwakyo.
17 Era eggaali baalikimanga nga baliggya mu Misiri nga lijjirira (sekeri) lukaaga eza ffeeza, n'embalaasi ng'ejjirira kikumi mu ataano; era bassekabaka bonna ab'Abakiiti bwe batyo ne bassekabaka ab'e Busuuli, baaziggyangamu mu mukono gwabwe.


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Okusaba kwa Nekkemiya
11:1 Nek 10:1; Zek 7:1Ebigambo bya Nekkemiya mutabani wa Kakaliya:
Awo mu mwezi gwa Kisuleevu mu mwaka ogw’amakumi abiri1:1 Bino byabaawo oluvannyuma lw’emyaka kyenda mu gumu (91), ng’abaawaŋŋangusibwa bakomyewo; nga mu mwaka 446 bc. bwe nnali nga ndi mu lubiri mu kibuga ekikulu ekya Susani,1:1 Susani ky’ekibuga bakabaka b’e Buperusi abasatu gye baabeeranga mu biseera eby’obutiti. Ekibuga ekyo kyali mu kiwonvu ky’omugga Tigiriisi. 21:2 a Nek 7:2 b Yer 52:28Kanani, omu ku baganda bange, n’ajja n’abamu ku basajja okuva mu Yuda, ne mubuuza ku bikwata ku kitundu ky’Abayudaaya ekyasigalawo, ne ku bifa mu Yerusaalemi. 31:3 2Bk 25:10; Nek 2:3, 13, 17Ne bantegeeza nti, “Abaawaŋŋangusibwa abaddayo mu ssaza1:3 Obwakabaka bwa Buperusi bwalina amasaza asatu. Essaza lya Yuda lyafugibwanga mu Samaliya. bali mu kabi kanene ne mu nnaku nnyingi; bbugwe wa Yerusaalemi yamenyebwa, era ne wankaaki waakyo yayokebwa omuliro.” 41:4 a Zab 137:1 b Ezr 9:4Awo bwe nawulira ebigambo ebyo, ne ntuula wansi ne nkaaba, ne mmala ebiro nga nnakuwadde, nga nsiiba era nga nsaba mu maaso ga Katonda w’eggulu. 51:5 a Ma 7:21; Nek 4:14 b Kuv 20:6; Dan 9:4Ne njogera nti,
“Ayi Mukama Katonda w’eggulu, Katonda omukulu ow’entiisa, akuuma endagaano ye, era ayagala abo abagondera amateeka ge. 61:6 a 1Bk 8:29 b Dan 9:17Ozibule amaaso go, otege okutu okuwulira okusaba kw’omuddu wo kwe nsaba mu maaso go emisana n’ekiro ku lwa baddu bo abantu ba Isirayiri. Njatula ebibi bye twakola, ffe Abayisirayiri, nga nange n’ennyumba ya kitange mwe tuli. 71:7 Ma 28:14-15; Zab 106:6Twasobya mu maaso go, ne tutagoberera mateeka go n’ebiragiro byo bye watuma omuddu wo Musa.
81:8 a 2Bk 20:3 b Lv 26:33“Jjukira ebiragiro bye wawa omuddu wo Musa, ng’oyogera nti, ‘Bwe mutaabeerenga beesigwa, ndibasaasaanya mu mawanga, 91:9 a Ma 30:4 b 1Bk 8:48; Yer 29:14naye bwe mulikyuka ne mukomawo gye ndi, ne mugondera amateeka gange, abantu bammwe abaawaŋŋangusibwa ne bwe banaabeeranga ku nkomerero y’eggulu, ndibakuŋŋaanyayo ne mbaleeta mu kifo kye neeroboza okubeerangamu Erinnya lyange.’
101:10 Kuv 32:11; Ma 9:29“Abo be baddu bo era be bantu bo be wanunula n’amaanyi go amangi era n’omukono gwo ogw’amaanyi. 111:11 a nny 6 b Lub 40:1Ayi Mukama, otege okutu eri okusaba kw’omuddu wo n’eri okusaba kw’abaddu bo abatya erinnya lyo. Omuddu wo omusobozese okulaba ekisa mu maaso g’omusajja ono.”
Ebiro ebyo nnali musenero wa kabaka.
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ネヘミヤの祈り
1ハカルヤの子ネヘミヤの記録――
ペルシヤのアルタシャスタ王の時代,第二十年の第三の月のこと,私はシュシャンの宮殿で王に仕えていましたが, 2そこにハナニという名の同胞が,ユダヤから来た人々といっしょに訪ねて来ました.この時とばかり,私はエルサレムの様子を尋ねてみました.「捕囚の地からエルサレムに戻った人々は元気にやっていますか.」 3「実は,大変な目に会っています.城壁はくずされたまま,門も焼き払われたままです.」
4私はそれを聞いて,座りこんで泣きました.そしてそれから何日も断食して,天の神にひたすら祈り続けました. 5「ああ,主なる神様.あなたを愛し,あなたに従う者に対して約束されたことを果たし,愛と思いやりを示してくださる,畏れかしこむべき神様.どうか,この祈りをお聞きください. 6-7私の訴えに耳を傾けてください.夜も昼もイスラエル国民のために祈っている私に,目を留めてください.確かに私たちは罪を犯しました.あなたがあなたのしもべモーセによってお与えくださった戒めを破るという恐ろしい罪を犯してしまったのです. 8しかし神様.あなたはモーセに,こうお語りになったではありませんか.『もしあなたがたが罪を犯すなら,わたしはあなたがたを国々に散らす. 9しかし,わたしのもとに立ち返り,わたしのおきてに従うなら,たとえ地の果てからでも,あなたがたをエルサレムへ連れ戻そう.エルサレムこそ,わたしが住む場所として選んだ地だからだ.』
10私たちはあなたに仕える者です.あなたの偉大な御力によって救われた国民です. 11主よ,どうか私の祈りを聞き入れてください.神様を敬うことを喜びとする者の祈りに,耳を傾けてください.王のもとに行き,嘆願をしますので,どうかお助けください.王が寛容な処置をしてくれるよう,王の心に働きかけてください.」当時,私は王の献酌官(王に酌をする重要な官吏)をしていました.